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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse WW domain-containing oxidoreductase

SKU : BHE13811129

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2982m
Alternative Names	Wox1
Categories	Elisa
Function	Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm (By similarity). May also play a role in tumor necrosis factor (TNF)-mediated cell death. Required for normal bone development.
Specificity	Natural and recombinant Mouse WW domain-containing oxidoreductase
Subcellular Location	Cytoplasm Nucleus Mitochondrion Partially localizes to the mitochondria (By similarity). Translocates to the nucleus in response to TGFB1 (By similarity). Translocates to the nucleus upon genotoxic stress or TNF stimulation.
Entryname	WWOX_MOUSE
Platform	PF00106
Protein Name	WW domain-containing oxidoreductase
Sequence	50: MAALRYAGLD ; DTDSEDELPP ; GWEERTTKDG ; WVYYANHTEE ; KTQWEHPKTG ; 100: KRKRVAGDLP ; YGWEQETDEN ; GQVFFVDHIN ; KRTTYLDPRL ; AFTVDDNPTK ; 150: PTTRQRYDGS ; TTAMEILQGR ; DFTGKVVLVT ; GANSGIGFET ; AKSFALHGAH ; 200: VILACRNLSR ; ASEAVSRILE ; EWHKAKVEAM ; TLDLAVLRSV ; QHFAEAFKAK ; 250: NVSLHVLVCN ; AGTFALPWGL ; TKDGLETTFQ ; VNHLGHFYLV ; QLLQDVLCRS ; 300: SPARVIVVSS ; ESHRFTDIND ; SSGKLDLSRL ; SPPRSDYWAM ; LAYNRSKLCN ; 350: ILFSNELHRR ; LSPRGVTSNA ; VHPGNMMYSA ; IHRNSWVYKL ; LFTLARPFTK ; 400: SMQQGAATTV ; YCAVAPELEG ; LGGMYFNNCC ; RCLPSEEAQS ; EETARALWEL ; 414: SERLIQDRLG ; SPSS
Sequence Length	414
String	Q91WL8
Sub Unit	Interacts with TP53, TP73/p73 and MAPK8. Interacts with MAPT/TAU. Forms a ternary complex with TP53 and MDM2 and interacts with ERBB4, LITAF and WBP1. May interact with COTE1 and SCOTIN (By similarity). Interacts with HYAL2 and RUNX2. Interacts with TNK2.

Uniprot	Q91WL8
Gene Name	Wwox
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:80707
Unigene	Mm.440420

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811129	E2982m	96T	$776		Add to Cart

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