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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 6

SKU : BHE13811391

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0030m
Alternative Names	Apo-1 antigen ; Apoptosis-mediating surface antigen FAS ; FASLG receptor ; CD95 ; Apt1 ; Tnfrsf6
Categories	Elisa
Function	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Specificity	Natural and recombinant Mouse Tumor necrosis factor receptor superfamily member 6
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	78-5000pg/mL
Entryname	TNR6_MOUSE
Method Type	Sandwich
Platform	PF00531
Protein Name	Tumor necrosis factor receptor superfamily member 6
Sensitivity	39.5pg/mL
Sequence	50: MLWIWAVLPL ; VLAGSQLRVH ; TQGTNSISES ; LKLRRRVRET ; DKNCSEGLYQ ; 100: GGPFCCQPCQ ; PGKKKVEDCK ; MNGGTPTCAP ; CTEGKEYMDK ; NHYADKCRRC ; 150: TLCDEEHGLE ; VETNCTLTQN ; TKCKCKPDFY ; CDSPGCEHCV ; RCASCEHGTL ; 200: EPCTATSNTN ; CRKQSPRNRL ; WLLTILVLLI ; PLVFIYRKYR ; KRKCWKRRQD ; 250: DPESRTSSRE ; TIPMNASNLS ; LSKYIPRIAE ; DMTIQEAKKF ; ARENNIKEGK ; 300: IDEIMHDSIQ ; DTAEQKVQLL ; LCWYQSHGKS ; DAYQDLIKGL ; KKAECRRTLD ; 327: KFQDMVQKDL ; GKSTPDTGNE ; NEGQCLE
Sequence Length	327
String	P25446
Sub Unit	Binds DAXX and RIPK1. Interacts with BRE and FEM1B (By similarity). Interacts with HIPK3. Part of a complex containing HIPK3 and FADD. Interacts with FADD.

Uniprot	P25446
Gene Name	Fas
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:14102
Unigene	Mm.1626

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811391	E0030m	96T	$776		Add to Cart

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