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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 16

SKU : BHE13811407

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9231m
Alternative Names	Low affinity neurotrophin receptor p75NTR ; Low-affinity nerve growth factor receptor ; NGF receptor ; CD271 ; Tnfrsf16
Categories	Elisa
Function	Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells (By similarity). Binds to rabies virus glycoprotein Gs.
Specificity	Natural and recombinant Mouse Tumor necrosis factor receptor superfamily member 16
Subcellular Location	Membrane Single-pass type I membrane protein
Entryname	TNR16_MOUSE
Platform	PF00531
Protein Name	Tumor necrosis factor receptor superfamily member 16
Sequence	50: MDRLRLLLLL ; LLLLGVSFGG ; AKETCSTGMY ; THSGECCKAC ; NLGEGVAQPC ; 100: GANQTVCEPC ; LDSVTFSDVV ; SATEPCKPCT ; ECLGLQSMSA ; PCVEADDAVC ; 150: RCSYGYYQDE ; ETGRCEACSV ; CGVGSGLVFS ; CQDKQNTVCE ; ECPEGTYSDE ; 200: ANHVDPCLPC ; TVCEDTERQL ; RECTPWADAE ; CEEIPGRWIT ; RSTPPEGSDV ; 250: TTPSTQEPEA ; PPERDLIAST ; VADTVTTVMG ; SSQPVVTRGT ; ADNLIPVYCS ; 300: ILAAVVVGLV ; AYIAFKRWNS ; CKQNKQGANS ; RPVNQTPPPE ; GEKLHSDSGI ; 350: SVDSQSLHDQ ; QTHTQTASAQ ; ALKGDGNLYS ; SLPLTKREEV ; EKLLNGDTWR ; 400: HLAGELGYQP ; EHIDSFTHEA ; CPVRALLASW ; GAQDSATLDA ; LLAALRRIQR ; 417: ADIVESLCSE ; STATSPV
Sequence Length	417
String	Q9Z0W1
Sub Unit	Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts with BEX1. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with NGFRAP1/BEX3. Interacts with KIDINS220 and NTRK1. Can form a ternary complex with NTRK1 and KIDINS220 and this complex is affected by the expression levels of KIDINS220. An increase in KIDINS220 expression leads to a decreased association of NGFR and NTRK1 (By similarity). Interacts with LINGO1.

Uniprot	Q9Z0W1
Gene Name	Ngfr
Immunogen Species	Mus musculus (Mouse)
Unigene	Mm.283893

Reference	1. "Low-affinity nerve-growth factor receptor (p75NTR) can serve as a receptor for rabies virus." Tuffereau C., Benejean J., Blondel D., Kieffer B., Flamand A. EMBO J.17:7250-7259(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: A. 2. "Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis." Mukai J., Shoji S., Kimura M.T., Okubo S., Sano H., Suvanto P., Li Y., Irie S., Sato T.-A. J. Biol. Chem.277:13973-13982(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NGFRAP1 3. "p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity." Baeza-Raja B., Li P., Le Moan N., Sachs B.D., Schachtrup C., Davalos D., Vagena E., Bridges D., Kim C., Saltiel A.R., Olefsky J.M., Akassoglou K. Proc. Natl. Acad. Sci. U.S.A.109:5838-5843(2012) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH RAB31 4. "p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks." Baeza-Raja B., Eckel-Mahan K., Zhang L., Vagena E., Tsigelny I.F., Sassone-Corsi P., Ptacek L.J., Akassoglou K. J. Neurosci.33:10221-10234(2013) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811407	E9231m	96T	$776		Add to Cart

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