Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells.
Specificity
Natural and recombinant Mouse Tumor necrosis factor receptor superfamily member 11A
Binds to the clefts between the subunits of the TNFSF11 ligand trimer to form a heterohexamer. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6 (By similarity). Interacts (via cytoplasmic domain) with GAB2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.01 ANGSTROMS) OF 26-210 ALONE AND IN COMPLEX WITH TNFSF11;DISULFIDE BONDS;FUNCTION;SODIUM-BINDING SITE;SUBUNIT
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 31-198 IN COMPLEX WITH TNFSF11/RANKL;DISULFIDE BONDS;GLYCOSYLATION AT ASN-106
Reviews of ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 11A