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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Transcription factor E2-alpha

SKU : BHE13811120

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14975m
Alternative Names	Immunoglobulin enhancer-binding factor E12/E47 ; Transcription factor 3 ; TCF-3 ; Transcription factor A1 ; Alf2 ; Me2 ; Tcfe2a
Categories	Elisa
Function	Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.
Specificity	Natural and recombinant Mouse Transcription factor E2-alpha
Subcellular Location	Nucleus
Entryname	TFE2_MOUSE
Method Type	Sandwich
Platform	PF00010
Protein Name	Transcription factor E2-alpha
Sequence	50: MMNQSQRMAP ; VGSDKELSDL ; LDFSMMFPLP ; VANGKSRPAS ; LGGTQFAGSG ; 100: LEDRPSSGSW ; GSSDQNSSSF ; DPSRTYSEGA ; HFSDSHSSLP ; PSTFLGAGLG ; 150: GKGSERNAYA ; TFGRDTSVGT ; LSQAGFLPGE ; LSLSSPGPLS ; PSGIKSSSQY ; 200: YPSFPSNPRR ; RAADGGLDTQ ; PKKVRKVPPG ; LPSSVYPPSS ; GDSYSRDAAA ; 250: YPSAKTPSSA ; YPSPFYVADG ; SLHPSAELWS ; TPSQVGFGPM ; LGDGSSPLPL ; 300: APGSSSVGSG ; TFGGLQQQDR ; MGYQLHGSEV ; NGSLPAVSSF ; SAAPGTYSGT ; 350: SGHTPPVSGA ; AAESLLGTRG ; TTASSSGDAL ; GKALASIYSP ; DHSSNNFSPS ; 400: PSTPVGSPQG ; LPGTSQWPRA ; GAPSALSPNY ; DAGLHGLSKM ; EDRLDEAIHV ; 450: LRSHAVGTAS ; DLHGLLPGHG ; ALTTSFTGPM ; SLGGRHAGLV ; GGSHPEEGLT ; 500: SGASLLHNHA ; SLPSQPSSLP ; DLSQRPPDSY ; SGLGRAGTTA ; GASEIKREEK ; 550: EDEEIASVAD ; AEEDKKDLKV ; PRTRTSPDED ; EDDLLPPEQK ; AEREKERRVA ; 600: NNARERLRVR ; DINEAFKELG ; RMCQLHLSSE ; KPQTKLLILH ; QAVAVILSLE ; 650: QQVRERNLNP ; KAACLKRREE ; EKVSGVVGDP ; QLALSAAHPG ; LGEAHNPAGH ; 651: L
Sequence Length	651
String	P15806
Sub Unit	Forms a heterodimer with TWIST2. Forms a heterodimer with NEUROD1; the heterodimer is inhibited in presence of ID2, but not NR0B2, to E-box element. Isoform E12 interacts with RALGAPA1 and FIGLA. Interacts with EP300. Efficient DNA binding requires dimerization with another bHLH protein (By similarity). Homodimer. Heterodimer. Interacts with PTF1A, TGFB1I1 and UBE2I. Component of a nuclear TAL-1 complex composed at least of CBFA2T3, LDB1, TAL1 and TCF3. Interacts with NEUROD2.

Uniprot	P15806
Gene Name	Tcf3
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:21423
Unigene	Mm.3406

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811120	E14975m	96T	$776		Add to Cart

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