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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Toll-like receptor 3

SKU : BHE13811133

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1989m
Alternative Names	CD283
Categories	Elisa
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Specificity	Natural and recombinant Mouse Toll-like receptor 3
Subcellular Location	Endoplasmic reticulum membrane Single-pass type I membrane protein Endosome membrane
Detection Range	78-5000pg/mL
Entryname	TLR3_MOUSE
Method Type	Sandwich
Platform	PF00560
Protein Name	Toll-like receptor 3
Sensitivity	30pg/mL
Sequence	50: MKGCSSYLMY ; SFGGLLSLWI ; LLVSSTNQCT ; VRYNVADCSH ; LKLTHIPDDL ; 100: PSNITVLNLT ; HNQLRRLPPT ; NFTRYSQLAI ; LDAGFNSISK ; LEPELCQILP ; 150: LLKVLNLQHN ; ELSQISDQTF ; VFCTNLTELD ; LMSNSIHKIK ; SNPFKNQKNL ; 200: IKLDLSHNGL ; SSTKLGTGVQ ; LENLQELLLA ; KNKILALRSE ; ELEFLGNSSL ; 250: RKLDLSSNPL ; KEFSPGCFQT ; IGKLFALLLN ; NAQLNPHLTE ; KLCWELSNTS ; 300: IQNLSLANNQ ; LLATSESTFS ; GLKWTNLTQL ; DLSYNNLHDV ; GNGSFSYLPS ; 350: LRYLSLEYNN ; IQRLSPRSFY ; GLSNLRYLSL ; KRAFTKQSVS ; LASHPNIDDF ; 400: SFQWLKYLEY ; LNMDDNNIPS ; TKSNTFTGLV ; SLKYLSLSKT ; FTSLQTLTNE ; 450: TFVSLAHSPL ; LTLNLTKNHI ; SKIANGTFSW ; LGQLRILDLG ; LNEIEQKLSG ; 500: QEWRGLRNIF ; EIYLSYNKYL ; QLSTSSFALV ; PSLQRLMLRR ; VALKNVDISP ; 550: SPFRPLRNLT ; ILDLSNNNIA ; NINEDLLEGL ; ENLEILDFQH ; NNLARLWKRA ; 600: NPGGPVNFLK ; GLSHLHILNL ; ESNGLDEIPV ; GVFKNLFELK ; SINLGLNNLN ; 650: KLEPFIFDDQ ; TSLRSLNLQK ; NLITSVEKDV ; FGPPFQNLNS ; LDMRFNPFDC ; 700: TCESISWFVN ; WINQTHTNIS ; ELSTHYLCNT ; PHHYYGFPLK ; LFDTSSCKDS ; 750: APFELLFIIS ; TSMLLVFILV ; VLLIHIEGWR ; ISFYWNVSVH ; RILGFKEIDT ; 800: QAEQFEYTAY ; IIHAHKDRDW ; VWEHFSPMEE ; QDQSLKFCLE ; ERDFEAGVLG ; 850: LEAIVNSIKR ; SRKIIFVITH ; HLLKDPLCRR ; FKVHHAVQQA ; IEQNLDSIIL ; 900: IFLQNIPDYK ; LNHALCLRRG ; MFKSHCILNW ; PVQKERINAF ; HHKLQVALGS ; 905: RNSAH
Sequence Length	905
String	Q99MB1
Sub Unit	Binds MYD88 via their respective TIR domains. Interacts with TICAM1. Homodimer formation is triggered by ligand binding and is required for TLR3 signaling. Binding of double-stranded RNA is required for the interaction with SRC (By similarity). Interacts (via transmembrane domain) with UNC93B1.

Uniprot	Q99MB1
Gene Name	Tlr3
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:142980
Unigene	Mm.33874

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811133	E1989m	96T	$776		Add to Cart

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