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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse SUMO-conjugating enzyme UBC9

SKU : BHE13810532

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11134m
Alternative Names	RING-type E3 SUMO transferase UBC9 ; SUMO-protein ligase ; Ubiquitin carrier protein 9 ; mUBC9 ; Ubiquitin carrier protein I ; Ubiquitin-conjugating enzyme E2 I ; Ubiquitin-protein ligase I ; Ubc9 ; Ubce2i ; Ubce9
Categories	Elisa
Function	Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly-SUMO chains. Essential for nuclear architecture, chromosome segregation and embryonic viability. Necessary for sumoylation of FOXL2 and KAT5.
Specificity	Natural and recombinant Mouse SUMO-conjugating enzyme UBC9
Subcellular Location	Nucleus Cytoplasm Mainly nuclear. In spermatocytes, localizes in synaptonemal complexes. Recruited by BCL11A into the nuclear body.
Detection Range	0.312-20ng/mL
Entryname	UBC9_MOUSE
Method Type	Sandwich
Platform	PF00179
Protein Name	SUMO-conjugating enzyme UBC9
Sensitivity	0.159ng/mL
Sequence	50: MSGIALSRLA ; QERKAWRKDH ; PFGFVAVPTK ; NPDGTMNLMN ; WECAIPGKKG ; 100: TPWEGGLFKL ; RMLFKDDYPS ; SPPKCKFEPP ; LFHPNVYPSG ; TVCLSILEED ; 150: KDWRPAITIK ; QILLGIQELL ; NEPNIQDPAQ ; AEAYTIYCQN ; RVEYEKRVRA ; 158: QAKKFAPS
Sequence Length	158
String	P63280
Sub Unit	Forms a tight complex with RANGAP1 and RANBP2. Interacts with SIAH1 and PARP. Interacts with various transcription factors such as TFAP2A, TFAP2B, TFAP2C, AR, ETS1 and SOX4. Interacts with RASD2. Interacts with RWDD3; the interaction enhances the sumoylation of a number of proteins such as HIF1A and I-kappa-B. Interacts with FOXL2. Forms a complex with SENP6 and UBE2I in response to UV irradiation. Interacts with DNM1L (via its GTPase and B domains); the interaction promotes sumoylation of DNM1L, mainly in the B domain (By similarity). Interacts with HIPK1, HIPK2, PPM1J and TCF3. Interacts with Moloney murine leukemia virus CA and adenovirus type 5 and type 12 E1A. Interacts with NR2C1; the interaction promotes its sumoylation. Interacts with NFATC2IP; this inhibits formation of poly-SUMO chains.

Uniprot	P63280
Gene Name	Ube2i
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:100044900
Unigene	Mm.240044

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810532	E11134m	96T	$776		Add to Cart

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