Glucose transporter type 8 ; GLUT-8 ; Glucose transporter type X1 ; Glut8 ; GlutX1
Categories
Elisa
Function
Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose.
Specificity
Natural and recombinant Mouse Solute carrier family 2, facilitated glucose transporter member 8
Subcellular Location
Cell membrane Multi-pass membrane protein Cytoplasmic vesicle membrane Multi-pass membrane protein Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration (By similarity). Insulin induces a change in the intracellular localization and gives rise to insertion in the plasma membrane.