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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse SLAM family member 5

SKU : BHE13809517

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9091m
Antigen	CD84
Alternative Names	Leukocyte differentiation antigen CD84 ; Signaling lymphocytic activation molecule 5 ; CD84 ; Slamf5
Categories	Elisa
Function	Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain-containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells.
Specificity	Natural and recombinant Mouse SLAM family member 5
Subcellular Location	Cell membrane Single-pass type I membrane protein
Entryname	SLAF5_MOUSE
Platform	PF07686
Protein Name	SLAM family member 5
Sequence	50: MAQRHLWIWF ; LCLQTWSEAA ; GKDADPMVMN ; GILGESVTFL ; LNIQEPKKID ; 100: NIAWTSQSSV ; AFIKPGVNKA ; EVTITQGTYK ; GRIEIIDQKY ; DLVIRDLRME ; 150: DAGTYKADIN ; EENEETITKI ; YYLHIYRRLK ; TPKITQSLIS ; SLNNTCNITL ; 200: TCSVEKEEKD ; VTYSWSPFGE ; KSNVLQIVHS ; PMDQKLTYTC ; TAQNPVSNSS ; 250: DSVTVQQPCT ; DTPSFHPRHA ; VLPGGLAVLF ; LLILIPMLAF ; LFRLYKRRRD ; 300: RIVLEADDVS ; KKTVYAVVSR ; NAQPTESRIY ; DEIPQSKMLS ; CKEDPVTTIY ; 329: SSVQLSEKMK ; ETNMKDRSLP ; KALGNEIVV
Sequence Length	329
String	Q18PI6
Sub Unit	Homodimer; via its extracellular domain. Forms a head to tail dimer with a CD48 molecule from another cell. Interacts with SH2 domain-containing proteins SH2D1A/SAP and SH2D1B/hEAT-2. Interacts with tyrosine-protein phosphatases PTPN6 and PTPN11 via its phosphorylated cytoplasmic domain, and this interaction is blocked by SH2D1A.

Uniprot	Q18PI6
Gene Name	Cd84
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:12523
Unigene	Mm.259115

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809517	E9091m	96T	$776		Add to Cart

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