Activation-induced cytidine deaminase ; AID ; Cytidine aminohydrolase ; Aid
Categories
Elisa
Function
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating to DNA demethylation.
Specificity
Natural and recombinant Mouse Single-stranded DNA cytosine deaminase