ELISA Kit for Mouse Serotonin N-acetyltransferase

Mfr.No.	E1937m
Alternative Names	Aralkylamine N-acetyltransferase ; AA-NAT ; Snat
Categories	Elisa
Function	Catalyzes the N-acetylation of serotonin into N-acetylserotonin.
Specificity	Natural and recombinant Mouse Serotonin N-acetyltransferase
Subcellular Location	Cytoplasm
Detection Range	0.312-20ng/mL
Entryname	SNAT_MOUSE
Method Type	Sandwich
Platform	PF00583
Protein Name	Serotonin N-acetyltransferase
Sensitivity	0.183ng/mL
Sequence	50: MLNINSLKPE ; ALHLPLGTSE ; FLGCQRRHTL ; PASEFRCLTP ; EDATSAFEIE ; 100: REAFISVSGT ; CPLYLDEIRH ; FLTLCPELSL ; GWFEEGCLVA ; FIIGSLWDKE ; 150: RLTQESLTLH ; RPGGRTAHLH ; VLAVHRTFRQ ; QGKGSVLLWR ; YLHHLGSQPA ; 200: VRRAVLMCED ; ALVPFYEKFG ; FQAVGPCAIT ; VGSLTFTELQ ; CSLRCHAFLR ; 205: RNSGC
Sequence Length	205
String	O88816
Sub Unit	Monomer (By similarity). Interacts with YWHAZ; the interaction requires phosphorylation on Thr-29, and modulates the enzymatic activity of AANAT through preventing dephosphorylation and/or proteolysis and stabilizing substrate binding. Subsequently, a second molecule of AANAT can bind, via the phosphorylated Ser-203 site, the other YWHAZ monomer with similar effect.

Reference	1. "Molecular cloning of serotonin N-acetyltransferase gene from the mouse and its daily expression in the retina." Sakamoto K., Ishida N. Neurosci. Lett.250:181-184(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INDUCTION strain: BALB/c. tissue: Retina. 2. "Natural melatonin 'knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase." Roseboom P.H., Namboodiri M.A.A., Zimonjic D.B., Popescu N.C., Rodriguez I.R., Gastel J.A., Klein D.C. Brain Res. Mol. Brain Res.63:189-197(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];TISSUE SPECIFICITY;INDUCTION;IDENTIFICATION OF A TRUNCATED FORM IN C57BL/6 strain: 129/Sv. strain: C3H/He. tissue: Pineal gland. 3. "Genetic variation of melatonin productivity in laboratory mice under domestication." Kasahara T., Abe K., Mekada K., Yoshiki A., Kato T. Proc. Natl. Acad. Sci. U.S.A.107:6412-6417(2010) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION strain: C3H/He. strain: C57BL/6J. tissue: Pineal gland.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809812	E1937m	96T	$776		Add to Cart