Activin receptor-like kinase 1 ; ALK-1 ; TGF-B superfamily receptor type I ; TSR-I ; Acvrlk1 ; Alk-1
Categories
Elisa
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May bind activin as well.
Specificity
Natural and recombinant Mouse Serine/threonine-protein kinase receptor R3