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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Serglycin

SKU : BHE13810031

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1072m
Alternative Names	Mastocytoma proteoglycan core protein ; Secretory granule proteoglycan core protein ; gp600 ; Prg ; Prg1
Categories	Elisa
Function	Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.
Specificity	Natural and recombinant Mouse Serglycin
Subcellular Location	Cytoplasmic granule Secreted extracellular space Golgi apparatus Found in mast cell granules and in cytoplasmic granules of cytolytic T lymphocytes from where it is secreted upon cell activation. Secreted constitutively by endothelial cells and macrophages. Located to Golgi apparatus during neutrophil differentiation.
Detection Range	0.625-40ng/mL
Entryname	SRGN_MOUSE
Method Type	Sandwich
Platform	PF04360
Protein Name	Serglycin
Sensitivity	0.318ng/mL
Sequence	50: MQVPVGSRLV ; LALAFVLVWG ; SSVQGYPARR ; ARYQWVRCKP ; NGFFANCIEE ; 100: KGPQFDLIDE ; SNNIGPPMNN ; PVLMEGPSKD ; FISNYDDYGS ; GSGSGSGSGS ; 150: GSGSGSGSGF ; LGDMEWEYQP ; TDESNIVYFN ; YKPFDRILTE ; QNQDQPEDDF ; 152: II
Sequence Length	152
String	P13609
Sub Unit	Binds to activated CD44 and to GZMB.

Uniprot	P13609
Gene Name	Srgn
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:19073
Unigene	Mm.338790

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810031	E1072m	96T	$776		Add to Cart

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