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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Sequestosome-1

SKU : BHE13811319

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10081m
Alternative Names	STONE14 ; Ubiquitin-binding protein p62 ; A170 ; STAP
Categories	Elisa
Function	Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Adapter that mediates the interaction between TRAF6 and CYLD.
Specificity	Natural and recombinant Mouse Sequestosome-1
Subcellular Location	Cytoplasm Late endosome Nucleus Sarcomere. In cardiac muscles localizes to the sarcomeric band. Localizes to late endosomes. May also localize to the nucleus.
Detection Range	0.15 ng/mL -10.0 ng/mL
Entryname	SQSTM_MOUSE
Method Type	Sandwich
Platform	PF00564
Protein Name	Sequestosome-1
Sensitivity	0.083 ng/mL
Sequence	50: MASFTVKAYL ; LGKEEATREI ; RRFSFCFSPE ; PEAEAQAAAG ; PGPCERLLSR ; 100: VAVLFPTLRP ; GGFQAHYRDE ; DGDLVAFSSD ; EELTMAMSYV ; KDDIFRIYIK ; 150: EKKECRREHR ; PPCAQEAPRN ; MVHPNVICDG ; CNGPVVGTRY ; KCSVCPDYDL ; 200: CSVCEGKGLH ; REHSKLIFPN ; PFGHLSDSFS ; HSRWLRKLKH ; GHFGWPGWEM ; 250: GPPGNWSPRP ; PRAGDGRPCP ; TAESASAPPE ; DPNVNFLKNV ; GESVAAALSP ; 300: LGIEVDIDVE ; HGGKRSRLTP ; TTPESSSTGT ; EDKSNTQPSS ; CSSEVSKPDG ; 350: AGEGPAQSLT ; EQMKKIALES ; VGQPEEQMES ; GNCSGGDDDW ; THLSSKEVDP ; 400: STGELQSLQM ; PESEGPSSLD ; PSQEGPTGLK ; EAALYPHLPP ; EADPRLIESL ; 442: SQMLSMGFSD ; EGGWLTRLLQ ; TKNYDIGAAL ; DTIQYSKHPP ; PL
Sequence Length	442
String	Q64337
Sub Unit	Homooligomer or heterooligomer; may form homotypic arrays. Interacts directly with PRKCI and PRKCZ (Probable). Interacts with EBI3, LCK, RASA1, PRKCZ, PRKCI, NR2F2, NTRK1, NTRK2, NTRK3, NBR1, MAP2K5, TRIM55 and MAPKAPK5. Interacts with the proteasome subunits PSMD4 and PSMC2. Interacts with K63-polyubiquitinated MAPT/TAU. Interacts with IKBKB through PRKCZ and PRKCI. Interacts with NGFR through TRAF6 and bridges that complex to NTRK1. Forms a complex with MAP2K5 and PRKCZ or PRKCI. Component of a ternary complex with PAWR and PRKCZ. Upon TNF-alpha stimulation, interacts with RIPK1 problably bridging IKBKB to the TNF-R1 complex composed of TNF-R1/TNFRSF1A, TRADD and RIPK1. Forms a complex with JUB/Ajuba, PRKCZ and TRAF6. Forms ternary complexes with PRKCZ and KCNAB2 or PRKCZ and GABBR3. Interacts with KCNAB1, GABRR1, GABRR2 and GABRR3. Forms an NGF-induced complex with IKBKB, PRKCI and TRAF6 (By similarity). Interacts with TRAF6 and CYLD. Identified in a complex with TRAF6 and CYLD.

Uniprot	Q64337
Gene Name	Sqstm1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:18412
Unigene	Mm.40828

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811319	E10081m	96T	$776		Add to Cart

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