JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Retrotransposon-derived protein PEG10

SKU : BHE13808990

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E3142m
Alternative Names	Embryonal carcinoma differentiation regulated protein ; Mammalian retrotransposon-derived protein 2 ; Myelin expression factor 3 ; MyEF-3 ; Myelin expression factor 3-like protein 1 ; MEF3-like protein 1 ; Paternally expressed gene 10 protein ; Retrotransposon gag domain-containing protein 3 ; Retrotransposon-derived gag-like polyprotein ; Ty3/Gypsy-like protein ; Edr ; Mar2 ; Mart2 ; Mef3l1 ; Rgag3
Categories	Elisa
Function	May have a role in cell growth promotion, apoptotic resistance and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1 (By similarity). Involved at the immediate early stage of adipocyte differentiation. May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter.
Specificity	Natural and recombinant Mouse Retrotransposon-derived protein PEG10
Subcellular Location	Nucleus Cytoplasm Detected predominantly in the cytoplasm of breast and prostate carcinomas, in hepatocellular carcinoma (HCC) and B-cell chronic lymphocytic leukemia (B-CLL) cells. Colocalized with ALK1.
Detection Range	0.156-10ng/mL
Entryname	PEG10_MOUSE
Method Type	Sandwich
Platform	PF03732
Protein Name	Retrotransposon-derived protein PEG10
Sensitivity	0.092ng/mL
Sequence	50: MAAAGGSSNC ; PPPPPPPPPN ; NNNNNNTPKS ; PGVPDAEDDD ; ERRHDELPED ; 100: INNFDEDMNR ; QFENMNLLDQ ; VELLAQSYSL ; LDHLDDFDDD ; DEDDDFDPEP ; 150: DQDELPEYSD ; DDDLELQGAA ; AAPIPNFFSD ; DDCLEDLPEK ; FDGNPDMLGP ; 200: FMYQCQLFME ; KSTRDFSVDR ; IRVCFVTSML ; IGRAARWATA ; KLQRCTYLMH ; 250: NYTAFMMELK ; HVFEDPQRRE ; AAKRKIRRLR ; QGPGPVVDYS ; NAFQMIAQDL ; 300: DWTEPALMDQ ; FQEGLNPDIR ; AELSRQEAPK ; TLAALITACI ; HIERRLARDA ; 350: AAKPDPSPRA ; LVMPPNSQTD ; PTEPVGGARM ; RLSKEEKERR ; RKMNLCLYCG ; 400: NGGHFADTCP ; AKASKNSPPG ; KLPGPAVGGP ; SATGPERIRS ; PPSEASTQHL ; 450: QVMLQIHMPG ; RPTLFVRAMI ; DSGASGNFID ; QDFVIQNAIP ; LRIKDWPVMV ; 500: EAIDGHPIAS ; GPIILETHHL ; IVDLGDHREI ; LSFDVTQSPF ; FPIVLGIRWL ; 550: STHDPHITWS ; TRSIVFNSDY ; CRLRCRMFAQ ; IPSNLLFTVP ; QPNLHPYLLH ; 600: HVHPHVHPHM ; HQHLHQHLHQ ; FLHPDPHQYP ; HPDPHYHHHQ ; QADMQHQLQQ ; 650: YLYQYLYYHL ; YPVMHHHLPP ; DQHEHLHEYL ; HQYLHQYLHQ ; FLHHHLHPDL ; 700: HQYLYQYLHN ; HMNPDPHHHP ; HPDPPQDPHH ; PPHQDPHQHP ; DPHQDPPHQD ; 750: PHQDAHQDPH ; MDPHLHQHQH ; PQPQPHPQQH ; PNHPQQPPFF ; YHMAGFRIYH ; 800: PVRYYYIQNV ; YTPVDEHVYP ; GHRVVDPNIE ; MIPGAHSLPS ; GHLYSMSESE ; 850: MNALRNFVDR ; NVKDGLMTPT ; VAPNGAQVLQ ; VKRGWKLQVT ; YNCRAPQSGT ; 900: IQNQYLRMSL ; PNMGDPAHLA ; SYGEFVQVPG ; YPYPAYVYYT ; SPHMMTAWYP ; 950: VGRDVHGRII ; VVPVVITWSQ ; NTNRQPPVPQ ; YPPPQPPPPP ; PPPPPPPPPP ; 958: PASSCSAA
Sequence Length	958
Sub Unit	Interacts with ALK1, SIAH1 and SIAH2.

Uniprot	Q7TN75
Gene Name	Peg10
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:170676
Unigene	Mm.320575

Reference	1. "Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6." Ono R., Shiura H., Aburatani H., Kohda T., Kaneko-Ishino T., Ishino F. Genome Res.13:1696-1705(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: C57BL/6. 2. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 3. "Ty3/Gypsy retrotransposon fossils in mammalian genomes: did they evolve into new cellular functions?" Volff J., Korting C., Schartl M. Mol. Biol. Evol.18:266-270(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 146-661 strain: C57BL/6. 4. "MyEF-3, a developmentally controlled brain-derived nuclear protein which specifically interacts with myelin basic protein proximal regulatory sequences." Steplewski A., Krynska B., Tretiakova A., Haas S., Khalili K., Amini S. Biochem. Biophys. Res. Commun.243:295-301(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 132-364;DNA-BINDING 5. "Mammalian gene PEG10 expresses two reading frames by high efficiency -1 frameshifting in embryonic-associated tissues." Clark M.B., Jaenicke M., Gottesbuehren U., Kleffmann T., Legge M., Poole E.S., Tate W.P. J. Biol. Chem.282:37359-37369(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 310-329 AND 418-442;IDENTIFICATION BY MASS SPECTROMETRY;RIBOSOMAL FRAMESHIFT;DEVELOPMENTAL STAGE 6. "Identification and characterisation of a developmentally regulated mammalian gene that utilises -1 programmed ribosomal frameshifting." Shigemoto K., Brennan J., Walls E., Watson C.J., Stott D., Rigby P.W., Reith A.D. Nucleic Acids Res.29:4079-4088(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RIBOSOMAL FRAMESHIFT;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE 7. "PEG10 is a c-MYC target gene in cancer cells." Li C.-M., Margolin A.A., Salas M., Memeo L., Mansukhani M., Hibshoosh H., Szabolcs M., Klinakis A., Tycko B. Cancer Res.66:665-672(2006) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;TISSUE SPECIFICITY 8. "Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality." Ono R., Nakamura K., Inoue K., Naruse M., Usami T., Wakisaka-Saito N., Hino T., Suzuki-Migishima R., Ogonuki N., Miki H., Kohda T., Ogura A., Yokoyama M., Kaneko-Ishino T., Ishino F. Nat. Genet.38:101-106(2006) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE 9. "peg10, an imprinted gene, plays a crucial role in adipocyte differentiation." Hishida T., Naito K., Osada S., Nishizuka M., Imagawa M. FEBS Lett.581:4272-4278(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION;TISSUE SPECIFICITY

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13808990	E3142m	96T	$776		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.