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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Ras-related protein Rab-8A

SKU : BHE13809413

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14470m
Alternative Names	Oncogene c-mel ; Mel ; Rab8
Categories	Elisa
Function	May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization.
Specificity	Natural and recombinant Mouse Ras-related protein Rab-8A
Subcellular Location	Cell membrane Lipid-anchor Cytoplasmic side Golgi apparatus Cytoplasm perinuclear region Cell projection Colocalizes with OPTN at the Golgi complex and in vesicular structures close to the plasma membrane. In the GDP-bound form, present in the perinuclear region. Shows a polarized distribution to distal regions of cell protrusions in the GTP-bound form. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB11A in apical membrane initiation sites (AMIS) during the generation of apical surface and luminogenesis.
Detection Range	0.312-20ng/mL
Entryname	RAB8A_MOUSE
Method Type	Sandwich
Platform	PF00071
Protein Name	Ras-related protein Rab-8A
Sensitivity	0.166ng/mL
Sequence	50: MAKTYDYLFK ; LLLIGDSGVG ; KTCVLFRFSE ; DAFNSTFIST ; IGIDFKIRTI ; 100: ELDGKRIKLQ ; IWDTAGQERF ; RTITTAYYRG ; AMGIMLVYDI ; TNEKSFDNIR ; 150: NWIRNIEEHA ; SADVEKMILG ; NKCDVNDKRQ ; VSKERGEKLA ; LDYGIKFMET ; 200: SAKANINVEN ; AFFTLARDIK ; AKMDKKLEGN ; SPQGSSHGVK ; ITVEQQKRTS ; 207: FFRCSLL
Sequence Length	207
String	P55258
Sub Unit	Interacts with MAP4K2 and SYTL4. Interacts with SGSM1 and SGSM3 (By similarity). Interacts with OPTN. Interacts with RAB3IP. Interacts with MYO5B.

Uniprot	P55258
Gene Name	Rab8a
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:17274
Unigene	Mm.162811

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809413	E14470m	96T	$776		Add to Cart

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