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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse RAF proto-oncogene serine/threonine-protein kinase

SKU : BHE13809216

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9583m
Alternative Names	Proto-oncogene c-RAF ; cRaf ; Raf-1 ; Craf
Categories	Elisa
Function	Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3/MST2.
Specificity	Natural and recombinant Mouse RAF proto-oncogene serine/threonine-protein kinase
Subcellular Location	Cytoplasm Cell membrane Colocalizes with RGS14 and BRAF in both the cytoplasm and membranes.
Entryname	RAF1_MOUSE
Platform	PF00130
Protein Name	RAF proto-oncogene serine/threonine-protein kinase
Sequence	50: MEHIQGAWKT ; ISNGFGLKDA ; VFDGSSCISP ; TIVQQFGYQR ; RASDDGKLTD ; 100: SSKTSNTIRV ; FLPNKQRTVV ; NVRNGMSLHD ; CLMKALKVRG ; LQPECCAVFR ; 150: LLQEHKGKKA ; RLDWNTDAAS ; LIGEELQVDF ; LDHVPLTTHN ; FARKTFLKLA ; 200: FCDICQKFLL ; NGFRCQTCGY ; KFHEHCSTKV ; PTMCVDWSNI ; RQLLLFPNST ; 250: VGDSGVPAPP ; SFPMRRMRES ; VSRMPASSQH ; RYSTPHAFTF ; NTSSPSSEGS ; 300: LSQRQRSTST ; PNVHMVSTTL ; HVDSRMIEDA ; IRSHSESASP ; SALSSSPNNL ; 350: SPTGWSQPKT ; PVPAQRERAP ; GSGTQEKNKI ; RPRGQRDSSY ; YWEIEASEVM ; 400: LSTRIGSGSF ; GTVYKGKWHG ; DVAVKILKVV ; DPTPEQLQAF ; RNEVAVLRKT ; 450: RHVNILLFMG ; YMTKDNLAIV ; TQWCEGSSLY ; KHLHVQETKF ; QMFQLIDIAR ; 500: QTAQGMDYLH ; AKNIIHRDMK ; SNNIFLHEGL ; TVKIGDFGLA ; TVKSRWSGSQ ; 550: QVEQPTGSVL ; WMAPEVIRMQ ; DDNPFSFQSD ; VYSYGIVLYE ; LMAGELPYAH ; 600: INNRDQIIFM ; VGRGYASPDL ; SRLYKNCPKA ; MKRLVADCVK ; KVKEERPLFP ; 648: QILSSIELLQ ; HSLPKINRSA ; SEPSLHRAAH ; TEDINACTLT ; TSPRLPVF
Sequence Length	648
String	Q99N57
Sub Unit	Forms a multiprotein complex with Ras (M-Ras/MRAS), SHOC2 and protein phosphatase 1 (PPP1CA, PPP1CB and PPP1CC). Interacts with Ras proteins; the interaction is antagonized by RIN1. Weakly interacts with RIT1. Interacts (via N-terminus) with RGS14 (via RBD domains); the interaction mediates the formation of a ternary complex with BRAF, a ternary complex inhibited by GNAI1 (By similarity). Interacts with STK3/MST2; the interaction inhibits its pro-apoptotic activity. Interacts (when phosphorylated at Ser-259) with YWHAZ (unphosphorylated at 'Thr-232').

Uniprot	Q99N57
Gene Name	Raf1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:110157
Unigene	Mm.184163

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809216	E9583m	96T	$776		Add to Cart

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