Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Specificity
Natural and recombinant Mouse Poly [ADP-ribose] polymerase 2
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PARP1; XRCC1; POLB AND LRIG3;POLY-ADP-RIBOSYLATION
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-36 AND LYS-37;ADP-RIBOSYLATION AT LYS-36 AND LYS-37;MUTAGENESIS OF LYS-36 AND LYS-37
Reviews of ELISA Kit for Mouse Poly [ADP-ribose] polymerase 2