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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Platelet-derived growth factor C

SKU : BHE13808201

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0528m
Alternative Names	Fallotein ; Spinal cord-derived growth factor ; SCDGF ; VEGF-E ; Scdgf
Categories	Elisa
Function	Potent mitogen and chemoattractant for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. Appears to be involved in the three stages of wound healing: inflammation, proliferation and remodeling. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. Acts as a specific ligand for alpha platelet-derived growth factor receptor homodimer, and alpha and beta heterodimer. Binding to receptors induces their activation by tyrosine phosphorylation. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintainance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function. Seems to be involved in palatogenesis.
Specificity	Natural and recombinant Mouse Platelet-derived growth factor C
Subcellular Location	Cytoplasm Secreted Nucleus Cytoplasmic granule Sumoylated form is predominant in the nucleus. Stored in alpha granules in platelets (By similarity). Membrane associated when bound to receptors.
Detection Range	1.56-100ng/mL
Entryname	PDGFC_MOUSE
Method Type	Sandwich
Platform	PF00431
Protein Name	Platelet-derived growth factor C
Sensitivity	0.85ng/mL
Sequence	50: MLLLGLLLLT ; SALAGQRTGT ; RAESNLSSKL ; QLSSDKEQNG ; VQDPRHERVV ; 100: TISGNGSIHS ; PKFPHTYPRN ; MVLVWRLVAV ; DENVRIQLTF ; DERFGLEDPE ; 150: DDICKYDFVE ; VEEPSDGSVL ; GRWCGSGTVP ; GKQTSKGNHI ; RIRFVSDEYF ; 200: PSEPGFCIHY ; SIIMPQVTET ; TSPSVLPPSS ; LSLDLLNNAV ; TAFSTLEELI ; 250: RYLEPDRWQV ; DLDSLYKPTW ; QLLGKAFLYG ; KKSKVVNLNL ; LKEEVKLYSC ; 300: TPRNFSVSIR ; EELKRTDTIF ; WPGCLLVKRC ; GGNCACCLHN ; CNECQCVPRK ; 345: VTKKYHEVLQ ; LRPKTGVKGL ; HKSLTDVALE ; HHEECDCVCR ; GNAGG
Sequence Length	345
String	Q8CI19
Sub Unit	Homodimer; disulfide-linked (By similarity). Interacts (via CUB domain) with PLAT (via kringle domain).

Uniprot	Q8CI19
Gene Name	Pdgfc
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:54635
Unigene	Mm.331089

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808201	E0528m	96T	$776		Add to Cart

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