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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

SKU : BHE13809147

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E12686m
Alternative Names	Csk-binding protein ; Transmembrane phosphoprotein Cbp ; Cbp ; Pag
Categories	Elisa
Function	Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Specificity	Natural and recombinant Mouse Phosphoprotein associated with glycosphingolipid-enriched microdomains 1
Subcellular Location	Cell membrane Single-pass type III membrane protein Present in lipid rafts.
Entryname	PHAG1_MOUSE
Protein Name	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1
Sequence	50: MGPAGSVLSS ; GQMQMQMVLW ; GSLAAVAMFF ; LITFLVLLCS ; TCDREKKPRQ ; 100: HSGDHENLMN ; VPSDKDMFSH ; SATSLTTDAL ; ASSEQNGVLT ; NGDILSEDST ; 150: LTCMQHYEEV ; QTSASDLLDS ; QDSTGKAKCH ; QSRELPRIPP ; ENAVDEILTA ; 200: RAADTELGPG ; VEGPYEVLKD ; SSSQENMVED ; CLYETVKEIK ; EVADKGQGGK ; 250: SKSTSALKEL ; QGAPMEGKAD ; FAEYASVDRN ; KKCRHSANAE ; SILGTCSDLD ; 300: EESPPPVPVK ; LLDENANLPQ ; EGGGQAEEQA ; AEGTGGHSKR ; FSSLSYKSRE ; 350: EDPTLTEEEI ; SAMYSSVNKP ; GQSAHKPGPC ; MKGPESACHS ; MKGLPQRSSS ; 400: SCNDLYATVK ; DFEKTPNSIS ; TLPPARRPSE ; EPEPDYEAIQ ; TLNREDEKVP ; 429: LETNGHHVPK ; ESDYESIGDL ; QQCRDVTRL
Sequence Length	429
Sub Unit	When phosphorylated, interacts with CSK. Interacts with SLC9A3R1/EBP50. In resting T-cells, part of a PAG1-SLC9A3R1-MSN complex which is disrupted upon TCR activation.

Uniprot	Q3U1F9
Gene Name	Pag1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:94212
Unigene	Mm.23897

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809147	E12686m	96T	$776		Add to Cart

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