ELISA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear

Mfr.No.	E9951m
Alternative Names	Glutathione peroxidase 4 ; GPx-4
Categories	Elisa
Function	Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Stabilizes the condensed chromatin in sperm nuclei and is necessary for male fertility.
Specificity	Natural and recombinant Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
Subcellular Location	Nucleus
Detection Range	31.2-2000 pg/mL
Entryname	GPX42_MOUSE
Method Type	Sandwich
Platform	PF00255
Protein Name	Phospholipid hydroperoxide glutathione peroxidase, nuclear
Sensitivity	10 pg/mL
Sequence	50: MGRAAARKRG ; RCRQRGGSPR ; GRRRRGPGRQ ; SPRKRPGPRR ; RKARARRRRR ; 100: ARPRRMEPIP ; EPFNPGPLLQ ; EPPQYCNSSE ; FLGLCASRDD ; WRCARSMHEF ; 150: SAKDIDGHMV ; CLDKYRGFVC ; IVTNVASQUG ; KTDVNYTQLV ; DLHARYAECG ; 200: LRILAFPCNQ ; FGRQEPGSNQ ; EIKEFAAGYN ; VKFDMYSKIC ; VNGDDAHPLW ; 250: KWMKVQPKGR ; GMLGNAIKWN ; FTKFLIDKNG ; CEVKRYGPME ; EPQVIERDLP ; 253: CYL
Sequence Length	253
String	Q91XR9

Reference	1. "Identification of a specific sperm nuclei selenoenzyme necessary for protamine thiol cross-linking during sperm maturation." Pfeifer H., Conrad M., Roethlein D., Kyriakopoulos A., Brielmeier M., Bornkamm G.W., Behne D. FASEB J.15:1236-1238(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE;SUBCELLULAR LOCATION;TISSUE SPECIFICITY tissue: Testis. 2. "Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene." Imai H., Hirao F., Sakamoto T., Sekine K., Mizukura Y., Saito M., Kitamoto T., Hayasaka M., Hanaoka K., Nakagawa Y. Biochem. Biophys. Res. Commun.305:278-286(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] strain: 129/SvJ. tissue: Liver. 3. "The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults." Yant L.J., Ran Q., Rao L., Van Remmen H., Shibatani T., Belter J.G., Motta L., Richardson A., Prolla T.A. Free Radic. Biol. Med.34:496-502(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13804836	E9951m	96T	$776		Add to Cart