Peptidoglycan recognition protein I-alpha ; PGLYRPIalpha ; Peptidoglycan recognition protein intermediate alpha ; Gm420 ; Pgrpia
Categories
Elisa
Function
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Specificity
Natural and recombinant Mouse Peptidoglycan recognition protein 3