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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Orexin

SKU : BHE13808368

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0777m
Alternative Names	Hypocretin ; Hcrt ; Ox ; Ppox
Categories	Elisa
Function	Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
Specificity	Natural and recombinant Mouse Orexin
Subcellular Location	Rough endoplasmic reticulum Cytoplasmic vesicle Cell junction synapse Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
Detection Range	7.8-500pg/mL
Entryname	OREX_MOUSE
Method Type	Sandwich
Platform	PF02072
Protein Name	Orexin
Sensitivity	4.24pg/mL
Sequence	50: MNFPSTKVPW ; AAVTLLLLLL ; LPPALLSLGV ; DAQPLPDCCR ; QKTCSCRLYE ; 100: LLHGAGNHAA ; GILTLGKRRP ; GPPGLQGRLQ ; RLLQANGNHA ; AGILTMGRRA ; 130: GAELEPHPCS ; GRGCPTVTTT ; ALAPRGGSGV ;
Sequence Length	130
String	O55241

Uniprot	O55241
Gene Name	Hcrt
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:15171
Unigene	Mm.10096

Reference	1. "Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior." Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanaka H., Williams S.C., Richardson J.A., Kozlowski G.P., Wilson S., Arch J.R.S., Buckingham R.E., Haynes A.C., Carr S.A., Annan R.S., McNulty D.E., Liu W.-S., Terrett J.A., Elshourbagy N.A., Bergsma D.J., Yanagisawa M.more... Cell92:573-585(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity." de Lecea L., Kilduff T.S., Peyron C., Gao X.-B., Foye P.E., Danielson P.E., Fukuhara C., Battenberg E.L.F., Gautvik V.T., Bartlett F.S. II, Frankel W.N., van den Pol A.N., Bloom F.E., Gautvik K.M., Sutcliffe J.G. Proc. Natl. Acad. Sci. U.S.A.95:322-327(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: C57BL/6J. 3. "Hypocretin/orexin, sleep and narcolepsy." Hungs M., Mignot E. Bioessays23:397-408(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW 4. "To eat or to sleep? Orexin in the regulation of feeding and wakefulness." Willie J.T., Chemelli R.M., Sinton C.M., Yanagisawa M. Annu. Rev. Neurosci.24:429-458(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808368	E0777m	96T	$776		Add to Cart

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