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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Nuclear receptor subfamily 1 group I member 2

SKU : BHE13808275

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10641m
Antigen	NR1I2
Alternative Names	Orphan nuclear receptor PXR ; Pregnane X receptor ; Pxr
Categories	Elisa
Function	Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs. Response to specific ligands is species-specific, due to differences in the ligand-binding domain. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes (By similarity). Activated by naturally occurring steroids such as pregnenolone and progesterone, the cholesterol metabolite 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol, synthetic glucocorticoids and antiglucocorticoids and 16-alpha-carbonitrile (PCN).
Specificity	Natural and recombinant Mouse Nuclear receptor subfamily 1 group I member 2
Subcellular Location	Nucleus
Detection Range	0.156-10ng/mL
Entryname	NR1I2_MOUSE
Method Type	Sandwich
Platform	PF00104
Protein Name	Nuclear receptor subfamily 1 group I member 2
Sensitivity	0.091ng/mL
Sequence	50: MRPEESWSRV ; GLVQCEEADS ; ALEEPINVEE ; EDGGLQICRV ; CGDKANGYHF ; 100: NVMTCEGCKG ; FFRRAMKRNV ; RLRCPFRKGT ; CEITRKTRRQ ; CQACRLRKCL ; 150: ESGMKKEMIM ; SDAAVEQRRA ; LIKRKKREKI ; EAPPPGGQGL ; TEEQQALIQE ; 200: LMDAQMQTFD ; TTFSHFKDFR ; LPAVFHSGCE ; LPEFLQASLL ; EDPATWSQIM ; 250: KDRVPMKISL ; QLRGEDGSIW ; NYQPPSKSDG ; KEIIPLLPHL ; ADVSTYMFKG ; 300: VINFAKVISY ; FRDLPIEDQI ; SLLKGATFEM ; CILRFNTMFD ; TETGTWECGR ; 350: LAYCFEDPNG ; GFQKLLLDPL ; MKFHCMLKKL ; QLHKEEYVLM ; QAISLFSPDR ; 400: PGVVQRSVVD ; QLQERFALTL ; KAYIECSRPY ; PAHRFLFLKI ; MAVLTELRSI ; 431: NAQQTQQLLR ; IQDSHPFATP ; LMQELFSSTD ; G
Sequence Length	431
String	O54915
Sub Unit	Heterodimer with RXRA. Interacts with NCOA1.

Uniprot	O54915
Gene Name	Nr1i2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:18171
Unigene	Mm.8509

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808275	E10641m	96T	$776		Add to Cart

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