The short isoform interacts with the extended kappa 3 site of the TNF alpha promoter after Fc gamma RIII stimulation and participates in the induction of this cytokine. The long isoform is either inactive or represses the transcriptional activation.
Specificity
Natural and recombinant Mouse Nuclear factor erythroid 2-related factor 1
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 3);FUNCTION;PHOSPHORYLATION BY CKII
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE PROMOTER USAGE;IDENTIFICATION OF ISOFORM 2;FUNCTION;INTERACTION WITH MAFG;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
Reviews of ELISA Kit for Mouse Nuclear factor erythroid 2-related factor 1