ELISA Kit for Mouse Non-secretory ribonuclease

Mfr.No.	E0765m
Alternative Names	Eosinophil cationic-type ribonuclease 4 ; MR-4 ; Ribonuclease 2 ; RNase 2 ; Ear4
Categories	Elisa
Function	This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Possesses a wide variety of biological activities.
Specificity	Natural and recombinant Mouse Non-secretory ribonuclease
Subcellular Location	Lysosome Cytoplasmic granule Matrix of eosinophil's large specific granule.
Detection Range	78-5000pg/mL
Entryname	RNAS2_MOUSE
Method Type	Sandwich
Platform	PF00074
Protein Name	Non-secretory ribonuclease
Sensitivity	39.4pg/mL
Sequence	50: MGPKLLESRL ; CLLLLLGLVL ; MLASCQAQIL ; SQKFYTQHIY ; NSTYPRCDAV ; 100: MRVVNRYRPR ; CKDINTFLHT ; SFADVVAVCG ; HPNITCNNLT ; RKNCHASSFQ ; 150: VFITFCNLTM ; PTRICTQCRY ; QTTGSVKYYR ; VACENRTPQD ; TPMYPVVPVH ; 155: LDGTF
Sequence Length	155
String	O35291
Sub Unit	Interacts with and forms a tight 1:1 complex with RNH1. Dimerization of two such complexes may occur.

Reference	1. "Molecular cloning of four novel murine ribonuclease genes: unusual expansion within the ribonuclease A gene family." Batten D., Dyer K.D., Domachowske J.B., Rosenberg H.F. Nucleic Acids Res.25:4235-4239(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] tissue: Fibroblast. 2. "Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase." Ulrich M., Petre A., Youhnovski N., Proemm F., Schirle M., Schumm M., Pero R.S., Doyle A., Checkel J., Kita H., Thiyagarajan N., Acharya K.R., Schmid-Grendelmeier P., Simon H.-U., Schwarz H., Tsutsui M., Shimokawa H., Bellon G., Lee J.J., Przybylski M., Doering G.more... J. Biol. Chem.283:28629-28640(2008) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NITRATION

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810226	E0765m	96T	$776		Add to Cart