Patatin-like phospholipase domain-containing protein 6 ; Nte
Categories
Elisa
Function
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.
Specificity
Natural and recombinant Mouse Neuropathy target esterase
Subcellular Location
Endoplasmic reticulum membrane Single-pass type I membrane protein Cytoplasmic side Anchored to the cytoplasmic face of the endoplasmic reticulum by its amino-terminal transmembrane segment.