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ELISA Kit for Mouse Matrix metalloproteinase-16

SKU : BHE13806828

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1664m
Alternative Names	Membrane-type matrix metalloproteinase 3 ; MT-MMP 3 ; Membrane-type-3 matrix metalloproteinase ; MT3-MMP
Categories	Elisa
Function	Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Specificity	Natural and recombinant Mouse Matrix metalloproteinase-16
Subcellular Location	Cell membrane Single-pass type I membrane protein Extracellular side Localized at the cell surface of melanoma cells.
Detection Range	0.156-10ng/mL
Entryname	MMP16_MOUSE
Method Type	Sandwich
Platform	PF11857
Protein Name	Matrix metalloproteinase-16
Sensitivity	0.078ng/mL
Sequence	50: MILLAFSSGR ; RLDFVHRSGV ; FFLQTLLWIL ; CATVCGTEQY ; FNVEVWLQKY ; 100: GYLPPTDPRM ; SVLRSAETMQ ; SALAAMQQFY ; GINMTGKVDR ; NTIDWMKKPR ; 150: CGVPDQTRGS ; SKFNIRRKRY ; ALTGQKWQHK ; HITYSIKNVT ; PKVGDPETRR ; 200: AIRRAFDVWQ ; NVTPLTFEEV ; PYSELENGKR ; DVDITIIFAS ; GFHGDSSPFD ; 250: GEGGFLAHAY ; FPGPGIGGDT ; HFDSDEPWTL ; GNPNHDGNDL ; FLVAVHELGH ; 300: ALGLEHSNDP ; TAIMAPFYQY ; METDNFKLPN ; DDLQGIQKIY ; GPPDKIPPPT ; 350: RPLPTVPPHR ; SVPPADPRRH ; DRPKPPRPPT ; GRPSYPGAKP ; NICDGNFNTL ; 400: AILRREMFVF ; KDQWFWRVRN ; NRVMDGYPMQ ; ITYFWRGLPP ; SIDAVYENSD ; 450: GNFVFFKGNK ; YWVFKDTTLQ ; PGYPHDLITL ; GNGIPPHGID ; SAIWWEDVGK ; 500: TYFFKGDRYW ; RYSEEMKTMD ; PGYPKPITIW ; KGIPESPQGA ; FVHKENGFTY ; 550: FYKGKEYWKF ; NNQILKVEPG ; YPRSILKDFM ; GCDGPTDRDK ; EGLSPPDDVD ; 600: IVIKLDNTAS ; TVKAIAIVIP ; CILALCLLVL ; VYTVFQFKRK ; GTPRHILYCK ; 607: RSMQEWV
Sequence Length	607
String	Q9WTR0
Sub Unit	Interacts with CSPG4 through CSPG4 chondroitin sulfate glycosaminoglycan.

Uniprot	Q9WTR0
Gene Name	Mmp16
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:17389
Unigene	Mm.187315

Reference	1. Seiki M., Kinoh H. Submitted (1999-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Differential localization and Triton X-100 solubility of membrane-type matrix metalloproteinases 1-3." Budde P., Gatsios P., Nienaber N.T., Li H., Staege M.S., Graeve L., Heinrich P.C., Frey J. Submitted (2000-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: C57BL/6. tissue: Brain. 3. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (2005-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: 129. tissue: Mammary tumor.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806828	E1664m	96T	$776		Add to Cart

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