Fc gamma receptor IIB ; Fc-gamma RII ; IgG Fc receptor II beta ; Lymphocyte antigen 17 ; Ly-17 ; CD32 ; Fcgr2b ; Ly-17
Categories
Elisa
Function
Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.
Specificity
Natural and recombinant Mouse Low affinity immunoglobulin gamma Fc region receptor II
Subcellular Location
Isoform IIB3 Secreted Released as a soluble molecule.
Detection Range
0.312-20ng/ml
Entryname
FCGR2_MOUSE
Method Type
Sandwich
Protein Name
Low affinity immunoglobulin gamma Fc region receptor II
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 30-51 (ISOFORMS IIB1 AND IIB2)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE (ISOFORM IIB1)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM IIB1);VARIANTS
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 30-330 (ISOFORMS IIB1 AND IIB2)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-290; TYR-309 AND TYR-326
Reviews of ELISA Kit for Mouse Low affinity immunoglobulin gamma Fc region receptor II