May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Specificity
Natural and recombinant Mouse Leukocyte immunoglobulin-like receptor subfamily B member 3
Subcellular Location
Cell membrane Single-pass type I membrane protein
Entryname
LIRB3_MOUSE
Protein Name
Leukocyte immunoglobulin-like receptor subfamily B member 3
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF TYR-794 AND TYR-824;INTERACTION WITH PTPN6/SHP-1 AND PTPN11/SHP-2;SUBCELLULAR LOCATION
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION AT TYR-794 AND TYR-824 BY LYN;MUTAGENESIS OF TYR-794 AND TYR-824;INTERACTION WITH PTPN6/SHP-1 AND PTPN11/SHP-2;SUBCELLULAR LOCATION
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION BY LYN;INTERACTION WITH LYN AND PTPN6/SHP-1;TISSUE SPECIFICITY
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-684 AND SER-757;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
Reviews of ELISA Kit for Mouse Leukocyte immunoglobulin-like receptor subfamily B member 3