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ELISA Kit for Mouse Latent-transforming growth factor beta-binding protein 4

SKU : BHE13806159

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11075m
Categories	Elisa
Function	May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).
Specificity	Natural and recombinant Mouse Latent-transforming growth factor beta-binding protein 4
Subcellular Location	Secreted extracellular space extracellular matrix
Detection Range	78-5000pg/mL
Entryname	LTBP4_MOUSE
Method Type	Sandwich
Platform	PF07645
Protein Name	Latent-transforming growth factor beta-binding protein 4
Sensitivity	41.1pg/mL
Sequence	50: MRRPGLGGPC ; PLLLLLLLPA ; ATSASGSSPS ; PSPSPIEKAV ; VPSHQAGVAA ; 100: CHCCLDQTPK ; SSRCTRASCR ; VRNCPPAKCT ; GLEGCLTPTP ; SVPSPSRSPV ; 150: EKSQVSLNWQ ; PLTLQEARAL ; LRQRRPRGPW ; ARALLKRRPP ; HRAPAGQARV ; 200: LCPLICHNGG ; VCVKPDRCLC ; PPDFAGKFCQ ; LHSSGARPPA ; PAMPGLTRSV ; 250: YTMPLANHRD ; DEHGVASMVS ; VHVEHPQEAS ; VVVHQVERVS ; GPWEEANPEA ; 300: LARAEAAARA ; EAAAPYTVLA ; QSAPREDGYS ; DASGFGYCFR ; ELRGSECASP ; 350: LPGLRTQEVC ; CRGEGLAWGV ; HDCHPCAEHL ; RNSNQVSGPN ; GPCPPGFERV ; 400: NGSCVDVDEC ; ATGGRCQHGE ; CANTRGGYTC ; VCPDGFLLDS ; SRSSCISQHV ; 450: ISEAKGPCYR ; VLHDGGCSLP ; ILRNITKQIC ; CCSRVGKAWG ; RGCQLCPPYG ; 500: SEGFREICPA ; GPGYHYSASD ; LRYNTRPLNQ ; DPPRVTFNQP ; RVPPATPRPP ; 550: TGFLPTRRPE ; PRPDPGPQPE ; PRPRPEPRPR ; PESRPRPEPR ; PRPEPRPQPE ; 600: SQPRPESRPR ; PESQPWPEFP ; LPSIPAWTGP ; EIPESGPSSS ; MCQRNPQVCG ; 650: PGRCVPRPSG ; YTCACDPGFR ; LGPQGTRCID ; IDECRRVPTP ; CAPGRCENTP ; 700: GSFRCVCGTG ; FQAGPRATEC ; LDVDECRRVP ; PPCDRGRCEN ; TPGSFLCVCP ; 750: AGYQAAPHGA ; SCQDVDECTQ ; SPGLCGRGVC ; ENLPGSFRCV ; CPAGFRGSAC ; 800: EEDVDECAQQ ; PPPCGPGRCD ; NTAGSFHCAC ; PAGFRSRGPG ; APCQDVDECS ; 850: RSPSPCAYGR ; CENTEGSFKC ; VCPTGFQPNA ; AGSECEDVDE ; CENRLACPGQ ; 900: ECVNSPGSFQ ; CRACPVGHHL ; HRGRCTDVDE ; CSSGTPCGLH ; GQCTNTKGSF ; 950: HCSCSTGYRA ; PSGQPGPCAD ; INECLEGDFC ; FPHGECLNTD ; GSFTCTCAPG ; 1000: YRPGPRGASC ; LDVDECSEED ; LCQSGICTNT ; DGSFECICPP ; GHRAGPDLAS ; 1050: CLDIDECRER ; GPALCGSQRC ; ENSPGSYRCV ; RDCDPGYHPG ; PEGTCDDIDE ; 1100: CREYGSAICG ; AQRCENTPGS ; YRCTPACDPG ; YQPTPGGGCQ ; DVDECRNRSF ; 1150: CGAHAMCQNL ; PGSFQCVCDQ ; GYEGARDGRH ; CVDVNECETL ; QGVCGSALCE ; 1200: NVEGSFLCVC ; PNSPEEFDPM ; TGRCVPPRAP ; AGTFPGSQPQ ; APASPSLPAR ; 1250: PPAPPPPRRP ; SPPRQGPVSS ; GRRECYFDTA ; APDACDNILA ; RNVTWQECCC ; 1300: TVGEGWGSGC ; RIQQCPGTET ; AEYQSLCPHG ; RGYLVPSGDL ; SARRDVDECQ ; 1350: LFQDQVCKSG ; VCVNTAPGYS ; CYCSNGFYYH ; AHRLECVDND ; ECADEEPACE ; 1400: GGRCVNTVGS ; YHCTCEPPLV ; LDGSRRRCVS ; NESQSLDDNL ; GVCWQEVGPD ; 1450: LVCSRPRLDR ; QATYTECCCL ; YGEAWGMDCA ; LCPAQDSDDF ; EALCNVLRPP ; 1500: AYGPPRPGGF ; GIPYEYGPDI ; GPPYQSLPYG ; PDLYPPPVLP ; YDPYPPPPGP ; 1550: FARREAPYGA ; PPFDMPDFED ; DGGPYGESET ; PDPPSRGTGW ; PYRSRDTRGS ; 1600: FPEPEESSER ; GSYTGALSEP ; YEGLEAEECG ; ILDGCPHGRC ; VRVPEGFTCD ; 1650: CFDGYRLDIT ; RMSCVDVNEC ; DEAEATSPLC ; VNARCVNTDG ; SFRCICRPGF ; 1666: APTHQPHHCA ; PARPRA
Sequence Length	1666
String	Q8K4G1
Sub Unit	Forms part of the large latent transforming growth factor beta precursor complex; removal is essential for activation of complex. Interacts with LTBP1 AND TGFB1. Binds to FBN1.

Uniprot	Q8K4G1
Gene Name	Ltbp4
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:108075
Unigene	Mm.272251

Reference	1. "Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer." Sterner-Kock A., Thorey I.S., Koli K., Wempe F., Otte J., Bangsow T., Kuhlmeier K., Kirchner T., Jin S., Keski-Oja J., von Melchner H. Genes Dev.16:2264-2273(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);DISRUPTION PHENOTYPE 2. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 60-1666 (ISOFORM 3) strain: C57BL/6. tissue: Brain. 4. "Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development." Urban Z., Hucthagowder V., Schuermann N., Todorovic V., Zilberberg L., Choi J., Sens C., Brown C.W., Clark R.D., Holland K.E., Marble M., Sakai L.Y., Dabovic B., Rifkin D.B., Davis E.C. Am. J. Hum. Genet.85:593-605(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806159	E11075m	96T	$776		Add to Cart

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