Cysteine-rich BMP regulator 2 ; Cysteine-rich motor neuron 2 protein ; CRIM-2 ; Kielin/chordin-like protein 1 ; KCP-1 ; Crim2 ; Kcp1
Categories
Elisa
Function
Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways.
Specificity
Natural and recombinant Mouse Kielin/chordin-like protein
Interacts with BMP7 and, by doing so, enhances binding to the type I receptors that contains cytoplasmic serine-/threonine protein kinase domains. Also able to interact with activin-A and TGFB1.