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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Interferon-induced protein 44-like

SKU : BHE13805080

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15342m
Alternative Names	H28
Categories	Elisa
Function	Precursor of the histocompatibility antigen HA-28 in BALB.B mice. More generally, minor histocompatibility antigens refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells. The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing. The binding of these peptides to MHC molecules and its expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-host disease (GVHD). More specifically, HA-28 minor antigen is transcribed in the BALB.B donor but not in host C57BL/6 cells. HA-28 is presented to the donor BALB.B cell surface by Kb MHC. This complex HA-28/Kb MHC elicits cytotoxic T-cell response in C57BL/6 mice immunized with BALB.B spleen cells. It induces C57BL/6 mice cells recognition and lysis by CD8 T-cell from BALB.B mice.
Specificity	Natural and recombinant Mouse Interferon-induced protein 44-like
Subcellular Location	Cytoplasm
Entryname	IF44L_MOUSE
Protein Name	Interferon-induced protein 44-like
Sequence	50: MKVTARLTWI ; EEKILEKLLG ; NASLTLLYQS ; SAHKNCVSEM ; TQKYSLQGST ; 100: MTVFHLEKDV ; VVGVFILENF ; PRLVSEKPCT ; CAWFSLKRNN ; SSGISALFLN ; 150: TKVIVDSEEL ; IIFSLDGLSL ; SVTPLRGFTL ; ALNDTVMNGL ; ELNLGHGFLP ; 200: VECEIFRVDG ; IKKNPSFIKK ; MVTAEQHRGK ; LLSALRAYKP ; YKDLVSEVRI ; 250: LLVGPVGSGK ; SSFFNSVKSA ; FQGHLTRQAI ; VGSDESSITK ; QYRVYSIKDG ; 300: KSGETLPFML ; CDSMGLEEGE ; EAGLCIDDIP ; HILQGCVPDR ; YQFNPCEPMK ; 350: PKHSPHAASP ; PLKDRIHCVA ; FVLHINSVNT ; LSDKMVAKLK ; KIRKDVVDCG ; 400: IGYVALLTNV ; EEYDEVLDDS ; FANMTETVTS ; LSQVQNVQKW ; LNIPIANILM ; 447: VSNYASERRL ; EPMKDILVFA ; ALRQMLRAAD ; DALEDLPLED ; TGNLAPF
Sequence Length	447
String	Q9BDB7
Sub Unit	HA-28 antigen forms a complex with Kb MHC in BALB.B donor cells.

Uniprot	Q9BDB7
Gene Name	Ifi44l
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:15061
Unigene	Mm.219544

Reference	1. "Differences that matter: major cytotoxic T cell-stimulating minor histocompatibility antigens." Malarkannan S., Horng T., Eden P., Gonzalez F., Shih P., Brouwenstijn N., Klinge H., Christianson G., Roopenian D., Shastri N. Immunity13:333-344(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION strain: BALB/c x BALB.B. strain: C57BL/6. tissue: Spleen. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2) strain: Czech II. tissue: Mammary tumor.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805080	E15342m	96T	$776		Add to Cart

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