JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Interferon-induced, double-stranded RNA-activated protein kinase

SKU : BHE13803306

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E1135m
Alternative Names	Eukaryotic translation initiation factor 2-alpha kinase 2 ; eIF-2A protein kinase 2 ; Interferon-inducible RNA-dependent protein kinase ; P1/eIF-2A protein kinase ; Protein kinase RNA-activated ; PKR ; Serine/threonine-protein kinase TIK ; Tyrosine-protein kinase EIF2AK2 ; 2.7.10.2 ; p68 kinase ; Pkr ; Prkr ; Tik
Categories	Elisa
Function	Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection. In adddition to serine/threonine-protein kinase activity, also has tyrosine-protein kinase activity: phosphorylates CDK1 upon DNA damage. CDK1 phosphorylation triggers CDK1 polyubiquitination and subsequent proteolysis, thus leading to G2 arrest.
Specificity	Natural and recombinant Mouse Interferon-induced, double-stranded RNA-activated protein kinase
Detection Range	0.312-20ng/mL
Entryname	E2AK2_MOUSE
Method Type	Sandwich
Platform	PF00035
Protein Name	Interferon-induced, double-stranded RNA-activated protein kinase
Sensitivity	0.157ng/mL
Sequence	50: MASDTPGFYM ; DKLNKYRQMH ; GVAITYKELS ; TSGPPHDRRF ; TFQVLIDEKE ; 100: FPEAKGRSKQ ; EARNAAAKLA ; VDILDNENKV ; DCHTSASEQG ; LFVGNYIGLV ; 150: NSFAQKKKLS ; VNYEQCEPNS ; ELPQRFICKC ; KIGQTMYGTG ; SGVTKQEAKQ ; 200: LAAKEAYQKL ; LKSPPKTAGT ; SSSVVTSTFS ; GFSSSSSMTS ; NGVSQSAPGS ; 250: FSSENVFTNG ; LGENKRKSGV ; KVSPDDVQRN ; KYTLDARFNS ; DFEDIEEIGL ; 300: GGFGQVFKAK ; HRIDGKRYAI ; KRVKYNTEKA ; EHEVQALAEL ; NHVNIVQYHS ; 350: CWEGVDYDPE ; HSMSDTSRYK ; TRCLFIQMEF ; CDKGTLEQWM ; RNRNQSKVDK ; 400: ALILDLYEQI ; VTGVEYIHSK ; GLIHRDLKPG ; NIFLVDERHI ; KIGDFGLATA ; 450: LENDGKSRTR ; RTGTLQYMSP ; EQLFLKHYGK ; EVDIFALGLI ; LAELLHTCFT ; 500: ESEKIKFFES ; LRKGDFSNDI ; FDNKEKSLLK ; KLLSEKPKDR ; PETSEILKTL ; 515: AEWRNISEKK ; KRNTC
Sequence Length	515
String	Q03963
Sub Unit	Homodimer. Interacts with DNAJC3 and STRBP (By similarity). Forms a complex with FANCA, FANCC, FANCG and HSP70.

Uniprot	Q03963
Gene Name	Eif2ak2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:19106
Unigene	Mm.378990

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13803306	E1135m	96T	$776		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.