Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
Specificity
Natural and recombinant Mouse Intelectin-1a
Subcellular Location
Cell membrane Lipid-anchor GPI-anchor Secreted Enriched in lipid rafts.