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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Integrin alpha-M

SKU : BHE13806171

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1685m
Alternative Names	CD11 antigen-like family member B ; CR-3 alpha chain ; Cell surface glycoprotein MAC-1 subunit alpha ; Leukocyte adhesion receptor MO1 ; CD11b
Categories	Elisa
Function	Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Alpha-M/beta-2 play a critical role in mast cell development and in immune complex-mediated glomerulonephritis. Mice expressing a null mutation of the alpha-M subunit gene demonstrate increase in neutrophil accumulation, in response to a impaired degranulation and phagocytosis, events that apparently accelerate apoptosis in neutrophils. These mice develop obesity.
Specificity	Natural and recombinant Mouse Integrin alpha-M
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.156-10ng/mL
Entryname	ITAM_MOUSE
Method Type	Sandwich
Platform	PF01839
Protein Name	Integrin alpha-M
Sensitivity	0.083ng/mL
Sequence	50: MTLKALLVTA ; LALCHGFNLD ; TEHPMTFQEN ; AKGFGQNVVQ ; LGGTSVVVAA ; 100: PQEAKAVNQT ; GALYQCDYST ; SRCHPIPLQV ; PPEAVNMSLG ; LSLAVSTVPQ ; 150: QLLACGPTVH ; QNCKENTYVN ; GLCYLFGSNL ; LRPPQQFPEA ; LRECPQQESD ; 200: IVFLIDGSGS ; INNIDFQKMK ; EFVSTVMEQF ; KKSKTLFSLM ; QYSDEFRIHF ; 250: TFNDFKRNPS ; PRSHVSPIKQ ; LNGRTKTASG ; IRKVVRELFH ; KTNGARENAA ; 300: KILVVITDGE ; KFGDPLDYKD ; VIPEADRAGV ; IRYVIGVGNA ; FNKPQSRREL ; 350: DTIASKPAGE ; HVFQVDNFEA ; LNTIQNQLQE ; KIFAIEGTQT ; GSTSSFEHEM ; 400: SQEGFSASIT ; SNGPLLGSVG ; SFDWAGGAFL ; YTSKDKVTFI ; NTTRVDSDMN ; 450: DAYLGYASAV ; ILRNRVQSLV ; LGAPRYQHIG ; LVVMFRENFG ; TWEPHTSIKG ; 500: SQIGSYFGAS ; LCSVDMDADG ; NTNLILIGAP ; HYYEKTRGGQ ; VSVCPLPRGR ; 550: ARWQCEALLH ; GDQGHPWGRF ; GAALTVLGDV ; NGDKLTDVAI ; GAPGEQENQG ; 600: AVYIFYGASI ; ASLSASHSHR ; IIGAHFSPGL ; QYFGQSLSGG ; KDLTMDGLMD ; 650: LAVGAQGHLL ; LLRAQPVLRL ; EATMEFSPKK ; VARSVFACQE ; QVLKNKDAGE ; 700: VRVCLRVRKN ; TKDRLREGDI ; QSTVTYDLAL ; DPVRSRIRAF ; FDETKNNTRR ; 750: RTQVFGLMQK ; CETLKLILPD ; CVDDSVSPII ; LRLNYTLVGE ; PLRSFGNLRP ; 800: VLAMDAQRFF ; TAMFPFEKNC ; GNDSICQDDL ; SITMSAMGLD ; TLVVGGPQDF ; 850: NMSVTLRNDG ; EDSYGTQVTV ; YYPSGLSYRK ; DSASQNPLTK ; KPWFVKPAES ; 900: SSSSEGHGAL ; KSTTWNINHP ; IFPANSEVTF ; NVTFDVDSHA ; SFGNKLLLKA ; 950: IVASENNMSR ; THKTKFQLEL ; PVKYAIYMIV ; TSDESSIRYL ; NFTASEMTSK ; 1000: VIQHQYQFNN ; LGQRSLPVSV ; VFWIPVQINN ; VTVWDHPQVI ; FSQNLSSACH ; 1050: TEQKSPPHSN ; FRDQLERTPV ; LNCSVAVCKR ; IQCDLPSFNT ; QEIFNVTLKG ; 1100: NLSFDWYIKT ; SHGHLLLVSS ; TEILFNDSAF ; ALLPGQESYV ; RSKTETKVEP ; 1150: YEVHNPVPLI ; VGSSIGGLVL ; LALITAGLYK ; LGFFKRQYKD ; MMNEAAPQDA ; 1153: PPQ
Sequence Length	1153
String	P05555
Sub Unit	Heterodimer of an alpha and a beta chain. Alpha-M associates with beta-2. Interacts with JAM3.

Uniprot	P05555
Gene Name	Itgam
Immunogen Species	Mus musculus (Mouse)
Unigene	Mm.262106

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806171	E1685m	96T	$776		Add to Cart

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