JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Integrator complex subunit 3

SKU : BHE13805780

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E0291m
Alternative Names	SOSS complex subunit A ; Sensor of single-strand DNA complex subunit A ; SOSS-A
Categories	Elisa
Function	Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.
Specificity	Natural and recombinant Mouse Integrator complex subunit 3
Subcellular Location	Nucleus Localizes to nuclear foci following DNA damage.
Detection Range	78-5000pg/mL
Entryname	INT3_MOUSE
Method Type	Sandwich
Platform	PF10189
Protein Name	Integrator complex subunit 3
Sensitivity	39pg/mL
Sequence	50: MELQKGKGTV ; AAAASGAAGG ; GGGGAGAGAP ; GGGRLLLSTS ; LDAKDELEER ; 100: LERCMSIVTS ; MTAGVSEREA ; NDALNAYVCK ; GPPQHEEICL ; GLFTLVLTEP ; 150: AQAQKCYRDL ; ALVSRDGMNI ; VLNKINQLLM ; EKYLKLQDTC ; RTQLVWLVRE ; 200: LVKSGVLGAD ; GVCMTFMKQI ; AGGDVTAKNI ; WLAESVLDIL ; TEQREWVLKS ; 250: SILIAMAVYT ; YLRLIVDHHG ; TAQLQTLRQK ; EVDFCISLLR ; ERFMECLMIG ; 300: RDLVRLLQNV ; ARIPEFELLW ; KDIIHNPQAL ; SPQFTGILQL ; LQSRTSRKFL ; 350: ACRLTPDMET ; KLLFMTSRVR ; FGQQKRYQDW ; FQRQYLSTPD ; SQSLRCDLIR ; 400: YICGVVHPSN ; EVLSSDILPR ; WAIIGWLLTT ; CTSNVAASNA ; KLALFYDWLF ; 450: FSPEKDSIMN ; IEPAILVMHH ; SMKPHPAITA ; TLLDFMCRII ; PNFYPPLEGH ; 500: VRQGVFSSLN ; HIVEKRVLAH ; LAPLFDNPKL ; DKELRSMLRE ; KFPEFCSSPS ; 550: PPVEVKIEEP ; VSMEMDNHLS ; DKDESCYDNA ; EAAFSDDEED ; LNSKGKKREF ; 600: RFHPIKETVV ; EEPVDVTPYL ; DQLDESLRDK ; VLQLQKGSDT ; EAQCEVMQEI ; 650: VDQVLEEDFD ; SEQLSVLASC ; LQELFKAHFR ; GEVLPEEVTE ; ESLEESVGKP ; 700: LYLIFRNLCQ ; MQEDNSSFSL ; LLDLLSELYQ ; KQPKIGYHLL ; YYLRASKAAA ; 750: GKMNLYESFA ; QATQLGDLHT ; CLMMDMKACQ ; EDDVRLLCHL ; TPSIYTEFPD ; 800: ETLRSGELLN ; MIVAVIDSAQ ; LQELVCHVMM ; GNLVMFRKDS ; VLNILIQSLD ; 850: WETFEQYCAW ; QLFLAHNIPL ; ETIIPILQHL ; KYKEHPEALS ; CLLLQLRREK ; 900: PSEEMVKMVL ; SRPCHPDDQF ; TTSILRHWCM ; KHDELLAEHI ; KALLIKNNSL ; 950: PRKRQSLRSS ; SSKLAQLTLE ; QILEHLDNLR ; LNLANTKQNF ; FSQTPILQAL ; 1000: QHVQASCDEA ; HKMKFSDLFS ; LAEEYEDSST ; KPPKSRRKAA ; LSSPRSRKNA ; 1041: TQPPNAEEES ; GSSSASEEED ; TKPKPTKRKR ; KGSSAVGSDS ; D
Sequence Length	1041
String	Q7TPD0
Sub Unit	Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Component of the SOSS complex, composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/SSBIP1. SOSS complexes containing SOSS-B1/OBFC2B are more abundant than complexes containing SOSS-B2/OBFC2A. Interacts with SOSS-B1/OBFC2B, SOSS-B2/OBFC2A and SOSS-C/SSBIP1; the interaction is direct. Interacts with NBN/NBS1.

Uniprot	Q7TPD0
Gene Name	Ints3
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:229543
Unigene	Mm.268564

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13805780	E0291m	96T	$776		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.