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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse High affinity immunoglobulin epsilon receptor subunit alpha

SKU : BHE13803814

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E8982m
Alternative Names	Fc-epsilon RI-alpha ; FcERI ; IgE Fc receptor subunit alpha ; Fce1a
Categories	Elisa
Function	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Specificity	Natural and recombinant Mouse High affinity immunoglobulin epsilon receptor subunit alpha
Subcellular Location	Cell membrane Single-pass type I membrane protein
Detection Range	78-5000pg/mL
Entryname	FCERA_MOUSE
Method Type	Sandwich
Protein Name	High affinity immunoglobulin epsilon receptor subunit alpha
Sensitivity	40.7pg/mL
Sequence	50: MVTGRSAQLC ; LALLFMSLDV ; ILTATEKSVL ; TLDPPWIRIF ; TGEKVTLSCY ; 100: GNNHLQMNST ; TKWIHNGTVS ; EVNSSHLVIV ; SATVQDSGKY ; ICQKQGLFKS ; 150: KPVYLNVTQD ; WLLLQTSADM ; ILVHGSFDIR ; CHGWKNWNVR ; KVIYYRNDHA ; 200: FNYSYESPVS ; IREATLNDSG ; TYHCKGYLRQ ; VEYESDKFRI ; AVVKAYKCKY ; 250:
Sequence Length	250
String	P20489
Sub Unit	Tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains.

Uniprot	P20489
Gene Name	Fcer1a
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:14125
Unigene	Mm.5266

Reference	1. "Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells." Ra C., Jouvin M.H.E., Kinet J.-P. J. Biol. Chem.264:15323-15327(1989) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 3. "mRNA variants encoding multiple forms of the high-affinity IgE receptor alpha subunit in transformed and nontransformed mast cells." Robertson M.W., Mehl V.S., Richards M.L., Liu F.T. Int. Arch. Allergy Appl. Immunol.96:289-295(1991) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 125-194 4. "Neural adrenergic/cyclic AMP regulation of the immunoglobulin E receptor alpha-subunit expression in the mammalian pinealocyte: a neuroendocrine/immune response link?" Ganguly S., Grodzki C., Sugden D., Moller M., Odom S., Gaildrat P., Gery I., Siraganian R.P., Rivera J., Klein D.C. J. Biol. Chem.282:32758-32764(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803814	E8982m	96T	$776		Add to Cart

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