Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
Specificity
Natural and recombinant Mouse Growth/differentiation factor 11
Subcellular Location
Secreted
Detection Range
15.6-1000pg/mL
Entryname
GDF11_MOUSE
Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of GDF11 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤4.3%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤6.9%
Protein Name
Growth/differentiation factor 11
Recovery
Recovery was determined by spiking various levels of GDF11 into serum and plasma .