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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Glutaredoxin-3

SKU : BHE13804868

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0509m
Alternative Names	PKC-interacting cousin of thioredoxin ; PICOT ; PKC-theta-interacting protein ; PKCq-interacting protein ; Thioredoxin-like protein 2 ; Picot ; Txnl2
Categories	Elisa
Function	Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. Has an essential function in embryogenesis.
Specificity	Natural and recombinant Mouse Glutaredoxin-3
Subcellular Location	Cytoplasm cell cortex Cytoplasm myofibril sarcomere Z line Under the plasma membrane. After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area (By similarity). In the Z line, found associated with CSRP3.
Detection Range	0.312-20ng/mL
Entryname	GLRX3_MOUSE
Method Type	Sandwich
Platform	PF00462
Protein Name	Glutaredoxin-3
Sensitivity	0.172ng/mL
Sequence	50: MAAGAAEAGE ; AAVAVVEVGS ; AQQFEELLRL ; KTKSLLVVHF ; WAPWAPQCVQ ; 100: MNDVMAELAK ; EHPHVSFVKL ; EAEAVPEVSE ; KYEISSVPTF ; LFFKNSQKVD ; 150: RLDGAHAPEL ; TKKVQRHVSS ; GAFPPSTNEH ; LKEDLSLRLK ; KLTHAAPCML ; 200: FMKGTPQEPR ; CGFSKQMVEI ; LHKHNIQFSS ; FDIFSDEEVR ; QGLKTYSNWP ; 250: TYPQLYVSGE ; LIGGLDIIKE ; LEASEELDTI ; CPKAPKLEER ; LKVLTNKASV ; 300: MLFMKGNKQE ; AKCGFSKQIL ; EILNSTGVEY ; ETFDILEDEE ; VRQGLKTFSN ; 337: WPTYPQLYVR ; GDLVGGLDIV ; KELKDNGELL ; PILKGEN
Sequence Length	337
String	Q9CQM9
Sub Unit	Monomer and homodimer; the homodimer is probably linked by 2 2Fe-2S clusters that may serve as a redox sensor. The monomer interacts with other proteins. Interacts (via N-terminus) with PRKCQ/PKC-theta (By similarity). Interacts (via C-terminus) with CSRP3. Interacts with CSRP2.

Uniprot	Q9CQM9
Gene Name	Glrx3
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:30926
Unigene	Mm.267692

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804868	E0509m	96T	$776		Add to Cart

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