ELISA Kit for Mouse G-protein coupled bile acid receptor 1

Mfr.No.	E15195m
Alternative Names	Membrane-type receptor for bile acids ; M-BAR ; Tgr5
Categories	Elisa
Function	Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids (By similarity). Involved in bile acid promoted GLP1R secretion.
Specificity	Natural and recombinant Mouse G-protein coupled bile acid receptor 1
Subcellular Location	Cell membrane Multi-pass membrane protein
Entryname	GPBAR_MOUSE
Platform	PF00001
Protein Name	G-protein coupled bile acid receptor 1
Sequence	50: MMTPNSTELS ; AIPMGVLGLS ; LALASLIVIA ; NLLLALGIAL ; DRHLRSPPAG ; 100: CFFLSLLLAG ; LLTGLALPML ; PGLWSRNHQG ; YWSCLLLHLT ; PNFCFLSLLA ; 150: NLLLVHGERY ; MAVLQPLRPH ; GSVRLALFLT ; WVSSLFFASL ; PALGWNHWSP ; 200: DANCSSQAVF ; PAPYLYLEVY ; GLLLPAVGAT ; ALLSVRVLAT ; AHRQLCEIRR ; 250: LERAVCRDVP ; STLARALTWR ; QARAQAGATL ; LFLLCWGPYV ; ATLLLSVLAY ; 300: ERRPPLGPGT ; LLSLISLGST ; SAAAVPVAMG ; LGDQRYTAPW ; RTAAQRCLRV ; 329: LRGRAKRDNP ; GPSTAYHTSS ; QCSIDLDLN
Sequence Length	329
String	Q80SS6

Reference	1. "Identification of membrane-type receptor for bile acids (M-BAR)." Maruyama T., Miyamoto Y., Nakamura T., Tamai Y., Okada H., Sugiyama E., Nakamura T., Itadani H., Tanaka K. Biochem. Biophys. Res. Commun.298:714-719(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "A G protein-coupled receptor responsive to bile acids." Kawamata Y., Fujii R., Hosoya M., Harada M., Yoshida H., Miwa M., Fukusumi S., Habata Y., Itoh T., Shintani Y., Hinuma S., Fujisawa Y., Fujino M. J. Biol. Chem.278:9435-9440(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 3. "Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1." Katsuma S., Hirasawa A., Tsujimoto G. Biochem. Biophys. Res. Commun.329:386-390(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13804033	E15195m	96T	$776		Add to Cart