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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Focal adhesion kinase 1

SKU : BHE13803857

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1178m
Alternative Names	Focal adhesion kinase-related nonkinase ; FRNK ; Protein-tyrosine kinase 2 ; p125FAK ; pp125FAK ; Fadk ; Fak ; Fak1 ; Kiaa4203
Categories	Elisa
Function	Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly (By similarity). Plays a potential role in oncogenic transformations resulting in increased kinase activity.
Specificity	Natural and recombinant Mouse Focal adhesion kinase 1
Subcellular Location	Cell junction focal adhesion Cell membrane Peripheral membrane protein Cytoplasmic side Constituent of focal adhesions.
Detection Range	78-5000pg/mL
Entryname	FAK1_MOUSE
Method Type	Sandwich
Platform	PF00373
Protein Name	Focal adhesion kinase 1
Sensitivity	40.3pg/mL
Sequence	50: MAAAYLDPNL ; NHTPSSSTKT ; HLGTGMERSP ; GAMERVLKVF ; HYFESSSEPT ; 100: TWASIIRHGD ; ATDVRGIIQK ; IVDSHKVKHV ; ACYGFRLSHL ; RSEEVHWLHV ; 150: DMGVSSVREK ; YELAHPPEEW ; KYELRIRYLP ; KGFLNQFTED ; KPTLNFFYQQ ; 200: VKSDYMQEIA ; DQVDQEIALK ; LGCLEIRRSY ; WEMRGNALEK ; KSNYEVLEKD ; 250: VGLKRFFPKS ; LLDSVKAKTL ; RKLIQQTFRQ ; FANLNREESI ; LKFFEILSPV ; 300: YRFDKECFKC ; ALGSSWIISV ; ELAIGPEEGI ; SYLTDKGCNP ; THLADFNQVQ ; 350: TIQYSNSEDK ; DRKGMLQLKI ; AGAPEPLTVT ; APSLTIAENM ; ADLIDGYCRL ; 400: VNGATQSFII ; RPQKEGERAL ; PSIPKLANSE ; KQGMRTHAVS ; VSHCQHKVKK ; 450: ARRFLPLVFC ; SLEPPPTDEI ; SGDETDDYAE ; IIDEEDTYTM ; PSKSYGIDEA ; 500: RDYEIQRERI ; ELGRCIGEGQ ; FGDVHQGVYL ; SPENPALAVA ; IKTCKNCTSD ; 550: SVREKFLQEA ; LTMRQFDHPH ; IVKLIGVITE ; NPVWIIMELC ; TLGELRSFLQ ; 600: VRKYSLDLAS ; LILYAYQLST ; ALAYLESKRF ; VHRDIAARNV ; LVSSNDCVKL ; 650: GDFGLSRYME ; DSTYYKASKG ; KLPIKWMAPE ; SINFRRFTSA ; SDVWMFGVCM ; 700: WEILMHGVKP ; FQGVKNNDVI ; GRIENGERLP ; MPPNCPPTLY ; SLMTKCWAYD ; 750: PSRRPRFTEL ; KAQLSTILEE ; EKVQQEERMR ; MESRRQATVS ; WDSGGSDEAP ; 800: PKPSRPGYPS ; PRSSEGFYPS ; PQHMVQTNHY ; QVSGYPGSHG ; IPAMAGSIYQ ; 850: GQASLLDQTE ; LWNHRPQEMS ; MWQPSVEDSA ; ALDLRGMGQV ; LPPHLMEERL ; 900: IRQQQEMEED ; QRWLEKEERF ; LKPDVRLSRG ; SIDREDGSFQ ; GPTGNQHIYQ ; 950: PVGKPDPAAP ; PKKPPRPGAP ; GHLSNLSSIS ; SPADSYNEGV ; KLQPQEISPP ; 1000: PTANLDRSND ; KVYENVTGLV ; KAVIEMSSKI ; QPAPPEEYVP ; MVKEVGLALR ; 1050: TLLATVDETI ; PALPASTHRE ; IEMAQKLLNS ; DLGELISKMK ; LAQQYVMTSL ; 1090: QQEYKKQMLT ; AAHALAVDAK ; NLLDVIDQAR ; LKMLGQTRPH ;
Sequence Length	1090
String	P34152
Sub Unit	Interacts with CAS family members. Interacts with GIT1. Component of a complex that contains at least FER, CTTN and PTK2/FAK. Interacts with BMX. Interacts with STEAP4. Interacts with ZFYVE21. Interacts with ESR1. Interacts with PIK3R1 or PIK3R2. Interacts with SRC. Interacts with EPHA2 (inactive form); participates to EPHA2 downstream signaling. Interacts with CD4; this interaction requires the presence of HIV-1 gp120. Interacts with EPHA1 (kinase activity-dependent) (By similarity). Interacts with SORBS1. Interacts with BCAR3. Interacts with RGNEF. Interacts with SHB. Interacts with PXN. Interacts with TGFB1I1.

Uniprot	P34152
Gene Name	Ptk2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:14083
Unigene	Mm.254494

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803857	E1178m	96T	$776		Add to Cart

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