Kindlin-3 ; Unc-112-related protein 2 ; Kind3 ; Urp2
Categories
Elisa
Function
Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs).
Specificity
Natural and recombinant Mouse Fermitin family homolog 3
Subcellular Location
Cell projection podosome Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;INTERACTION WITH ITGB1 AND ITGB3;MUTAGENESIS OF GLN-597
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;INTERACTION WITH ITGB2
Reviews of ELISA Kit for Mouse Fermitin family homolog 3