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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Fermitin family homolog 1

SKU : BHE13804285

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14765m
Alternative Names	Kindlin-1 ; Unc-112-related protein 1 ; Kind1 ; Urp1
Categories	Elisa
Function	Involved in cell adhesion. Contributes to integrin activation. When co-expressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites.
Specificity	Natural and recombinant Mouse Fermitin family homolog 1
Subcellular Location	Cytoplasm cytoskeleton Cell junction focal adhesion Cell projection ruffle membrane Peripheral membrane protein Cytoplasmic side Colocalizes with filamentous actin. Constituent of focal adhesions (By similarity). Localized at the basal aspect of skin keratinocytes, close to the cell membrane (By similarity). Upon TGFB1 treatment, it localizes to membrane ruffles.
Detection Range	78-5000pg/mL
Entryname	FERM1_MOUSE
Method Type	Sandwich
Platform	PF00373
Protein Name	Fermitin family homolog 1
Sensitivity	39.21pg/mL
Sequence	50: MLSSGDLTSA ; SWELVVRVDH ; ANGEQQTEIT ; LRVSGDLHIG ; GVMLKLVEQM ; 100: NIAQDWSDYA ; LWWEQKRCWL ; LKTHWTLDKC ; GVQADANLLF ; TPQHKMLRLR ; 150: LPNAKTVRLR ; VSFSAVVFKA ; VADICKVLNI ; RRPEELSLLK ; PSSDYCKKKK ; 200: KKEKNSKEPV ; IEDILNLESS ; STSSGSPVSP ; GLYSKTMTPT ; YDPINGTPAL ; 250: STMTWFGDSP ; LTEQNCSVLA ; FSQPPPSPDV ; LADMFQPRSL ; VDKAKMNAGW ; 300: LDSSRSLMEQ ; SIQEDEQLQL ; RFKYYTFFDL ; NPKYDAVRIN ; QLYEQARWAV ; 350: LLEEIDCTEE ; EMLIFAALQY ; HISKLSQCAE ; IQDFATKSEV ; DEVEAALSSL ; 400: EVTLEGGKAD ; NTLEDITDIP ; KLADYLKLFR ; PKKLMLKACK ; QYWFVFKDTS ; 450: IAYFKNKELE ; QGEPIEKLNL ; RGCEIVPDVN ; VSGRKFGIKL ; LIPVADGMNE ; 500: VYLRCDHEDQ ; YARWMAACIL ; ASKGKTMADS ; SYQPEVISIL ; SFLKMKNRNS ; 550: SPLVASSLEN ; MDMNPECLVS ; PCCAKKHKSK ; QLAARILEAH ; HNVAQMPLVE ; 600: AKLQFIQAWQ ; SLPEFGLTYY ; LVRFKGSKKD ; DILGVAYNRL ; IRIDAVTGIP ; 650: VTTWRFANMK ; QWNVNWEIRQ ; VAIEFDQNVS ; IAFTCLSADC ; KIVHEYIGGY ; 677: IFLSTRSKDQ ; NETLDEDLFH ; KLTGGQD
Sequence Length	677
String	P59113
Sub Unit	Interacts with the cytoplasmic domain of integrins ITGB1 and ITGB3.

Uniprot	P59113
Gene Name	Fermt1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:241639
Unigene	Mm.209784

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804285	E14765m	96T	$776		Add to Cart

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