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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Eukaryotic peptide chain release factor subunit 1

SKU : BHE13803912

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11482m
Categories	Elisa
Function	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (By similarity). Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Specificity	Natural and recombinant Mouse Eukaryotic peptide chain release factor subunit 1
Subcellular Location	Cytoplasm
Detection Range	0.312-20ng/ml
Entryname	ERF1_MOUSE
Method Type	Sandwich
Platform	PF03463
Protein Name	Eukaryotic peptide chain release factor subunit 1
Sensitivity	0.156ng/mL
Sequence	50: MADDPSAADR ; NVEIWKIKKL ; IKSLEAARGN ; GTSMISLIIP ; PKDQISRVAK ; 100: MLADEFGTAS ; NIKSRVNRLS ; VLGAITSVQQ ; RLKLYNKVPP ; NGLVVYCGTI ; 150: VTEEGKEKKV ; NIDFEPFKPI ; NTSLYLCDNK ; FHTEALTALL ; SDDSKFGFIV ; 200: IDGSGALFGT ; LQGNTREVLH ; KFTVDLPKKH ; GRGGQSALRF ; ARLRMEKRHN ; 250: YVRKVAETAV ; QLFISGDKVN ; VAGLVLAGSA ; DFKTELSQSD ; MFDQRLQSKV ; 300: LKLVDISYGG ; ENGFNQAIEL ; STEVLSNVKF ; IQEKKLIGRY ; FDEISQDTGK ; 350: YCFGVEDTLK ; ALEMGAVEIL ; IVYENLDIMR ; YVLHCQGTEE ; EKILYLTPEQ ; 400: EKDKSHFTDK ; ETGQEHELIE ; SMPLLEWFAN ; NYKKFGATLE ; IVTDKSQEGS ; 437: QFVKGFGGIG ; GILRYRVDFQ ; GMEYQGGDDE ; FFDLDDY
Sequence Length	437
String	Q8BWY3
Sub Unit	Heterodimer of two subunits, one of which binds GTP. Component of the transient SURF (SMG1-UPF1-eRF1-eRF3) complex (By similarity). Interacts with Moloney murine leukemia virus (MoLV) reverse transcriptase/Ribonuclease H p80 (via RT and RNase domains); this interaction is essential for translational readthrough of amber codon between viral gag and pol genes. Interacts with MoLV Gag-Pol precursor.

Uniprot	Q8BWY3
Gene Name	Etf1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:225363
Unigene	Mm.329353

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803912	E11482m	96T	$776		Add to Cart

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