Epithelial glycoprotein 314 ; EGP314 ; Protein 289A ; Tumor-associated calcium signal transducer 1 ; CD326 ; Tacstd1
Categories
Elisa
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Specificity
Natural and recombinant Mouse Epithelial cell adhesion molecule
Subcellular Location
Membrane Single-pass type I membrane protein Lateral cell membrane Cell junction tight junction Co-localizes with CLDN7 at the lateral cell membrane and tight junction.