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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Desmoplakin

SKU : BHE13803491

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15240m
Categories	Elisa
Function	Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
Specificity	Natural and recombinant Mouse Desmoplakin
Subcellular Location	Cell junction desmosome Cytoplasm cytoskeleton Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network.
Detection Range	78-5000pg/mL
Entryname	DESP_MOUSE
Method Type	Sandwich
Platform	PF00681
Protein Name	Desmoplakin
Sensitivity	34pg/mL
Sequence	50: MSCNGGSHPR ; INTLGRMTRA ; ESGPDLRYEM ; TYSGGGGGGG ; GGGGGGTSRT ; 100: FYSHSRRCTV ; NDQNSDGYCQ ; TGTMSRHQNQ ; NTIQEMLQNC ; SDCLMRAELI ; 150: AQPELKFGEG ; MQLAWNRELD ; EYFTQANDQM ; EIIDGLIREM ; RQMGQPCDAY ; 200: QKRLLQLQEQ ; MRALYKAISV ; PRVRRASSKG ; AGGYTCQSGS ; GWDEFTKRLT ; 250: GECLGWMRQQ ; REEMDLMAWG ; VDAGSVEQHI ; NSHRSIHNTI ; GDYRWQLDKI ; 300: KADLREKSAI ; YQLEEEYENL ; LKASFERMDH ; LRQLQNIIQA ; TSREIMWIND ; 350: CEEEELLYDW ; SDKNTNIAQK ; QEAFSIRMSQ ; LEVKEKELNK ; LKQESDQLVL ; 400: NQHPASDKIE ; AYMDTLQTQW ; SWILQITKCI ; DVHLKENAAY ; FQFFEEAQST ; 450: EAYLKGLQDS ; IRKKYPCDKN ; MPLQHLLEQI ; KELEKEREKI ; IEYKRQVQNL ; 500: VNKSKKIVQL ; KPRNPDYRSN ; KPIILRALCD ; YKQDQKIVHK ; GDECILKDNN ; 550: ERSKWYVTGP ; GGVDMLVPSV ; GLIIPPPNPL ; AVDLSCKIEQ ; YYEAILALWN ; 600: QLYINMKSLV ; SWHYCMIDIE ; KIRAMTIAKL ; KTMRQEDYMK ; TIEDLELHYQ ; 650: DFIKNSQGSE ; MFGDDDKRRM ; QSQFTDAQKH ; YQTLVIQLPG ; HPQHQTVTKT ; 700: EITHLGTCQD ; VNHNKVIETN ; RENDKQETWL ; LMELQKIRRQ ; MEHCEARMTL ; 750: KNLLLAEQGS ; THHITVKINE ; LKSVQNDSQA ; LAEVLNQLKD ; MLANFRGSEK ; 800: YCYLQNEIFG ; LFQKLENING ; VSDGYLNSLC ; SVRALLQAIL ; QTEDMLKVYE ; 850: ARLTEEETVC ; LDLDKVEAYR ; CGLKKIKNDL ; NLKKSLLATM ; KTELQKAQQI ; 900: HSQSSQQYPL ; YDLDLGKFTE ; KVTQLTDRWQ ; KIDKQIDFRL ; WDLEKQIKQL ; 950: RNYRDNYQSF ; CKWLYDAKRR ; QDSLESMKFG ; DSNTVMRFLN ; EQKNLHSEIS ; 1000: GKRDKSEEVH ; KIAELCANSI ; KDYELQLASY ; TSGLETLLNI ; PIKRTMVQSP ; 1050: SGVILQEAAD ; IHARYIELLT ; RSGDYYRFLS ; EMLKSLEDLK ; LKNTKIEVLE ; 1100: EELRLARDAN ; SENCNKNKFL ; DQNLQKYQAE ; CSQFKAKLVS ; LEELKRQAEL ; 1150: DGKSAKQNLD ; KCYGQIKELN ; EKITRLTYEI ; EDEKRRRKTV ; EDRFDQQKND ; 1200: YDQLQKARQC ; EKENLSWQKL ; ESEKAIKEKE ; YEIERLRVLL ; QEEGARKREY ; 1250: ENELAKVRNH ; YNEEMSNLRN ; KYETEINITK ; TTIKEISMQK ; EDDSKNLRNQ ; 1300: MDRLSRENRD ; LKDEIVRLND ; SILQATEQRR ; RAEENALQQK ; ACGSETMQKK ; 1350: QRLEIELKQV ; IQQRSEDNAR ; HKQSLEEAAK ; TIQDKNKEIE ; RLKAEYQEEA ; 1400: KRRWEYENEL ; SKVRNSYDEE ; IISLKNQFET ; EINITKTTIH ; QLTMQKEEDT ; 1450: SGYRAQIDNL ; TRENRSLCEE ; VKRLKNTLAQ ; TTENLRRVEE ; NAQQQKATGS ; 1500: EMSQRKQQLE ; IELRQVTQMR ; TEESMRYKQS ; LDDAAKTIQD ; KNKEIERLKQ ; 1550: LVDKETNERK ; CLEDENSKLQ ; RVQYDLQKAN ; NSATEAMSKL ; KVQEQELTRL ; 1600: RIDYERVSQE ; RTVKDQDITR ; IQSSLKDLQL ; QKQKAEEELS ; RLKRTASDES ; 1650: SKRKMLEEEL ; EAMRRSLKEQ ; AVKITNLTQQ ; LEQASIVKKR ; SEDDLRQQRD ; 1700: VLDGHVREKQ ; RTQEELRRLS ; LDVEALRRQL ; VQEQENVKQA ; HLRNEHFQKA ; 1750: IEDKSRSLNE ; SKIEIERLQS ; LTENLTKEHL ; MLEEELRNLR ; LEYDDLRRGR ; 1800: SEADSDKNST ; ISELRSQLQI ; SNNRTLELQG ; LINDLQRERE ; NLRQEIEKFQ ; 1850: KQALEASNRI ; QESKSQCTQV ; VQERESLLVK ; IKVLEQDKAR ; LQRLEDELNR ; 1900: AKATLEAESR ; VKQRLECEKQ ; QIQNDLNQWK ; TQYSRKEETI ; RKIESEREKS ; 1950: EREKNSLRSE ; IERLQAEIKR ; IEERCRRKLE ; DSSRETQSQL ; ESERCRLQKE ; 2000: IEKLRQRPYG ; SHRETQTEYE ; WTVDSSKLVF ; DGLRKKVTAM ; QLYECQLIDK ; 2050: TTLDKLLKGK ; KSVEEVASEI ; QPFLRGAGAI ; AGASASPKEK ; YSLVEAKRKK ; 2100: FITPESTVML ; LEAQAATGGI ; IDPHRNEKLT ; VDNAVARDLI ; DFDDRQQIYT ; 2150: AEKAITGFDD ; PFSGKTVSVS ; EAIKKNLIDR ; ETGMRLLEAQ ; LASGGVVDPV ; 2200: NSVFLPKDVA ; LARGLIDRDL ; YRSLNDPRDS ; QKNFVDPITK ; KKVSYMQLRE ; 2250: RCRIEPHTGL ; LLLSVQKRSM ; SFQGIRQPVT ; VTELVDSGIL ; RPSTVNELES ; 2300: GQISYDEVGE ; RIKDFLQGSS ; CIAGIYNETT ; KQKLGIYEAM ; KIGLVRPGTA ; 2350: LELLEAQAAT ; GFIVDPVSNL ; RLPVEEAYKR ; GLVGIEFKEK ; LLSAERAVTG ; 2400: YNDPETGNII ; SLFQAMNKEL ; IEKGHGIRLL ; EAQIATGGII ; DPKESHRLPV ; 2450: DMAYKRGYFN ; EELSEILSDP ; SDDTKGFFDP ; NTEENLTYLQ ; LKERCIKDEE ; 2500: TGLCLLPLKE ; KKKQVQTSQK ; NTLRKRRVVI ; VDPETNKEMS ; VQEAYKKGLI ; 2550: DYDTFKELCE ; QECEWEEITI ; TGSDGSTRVV ; LVDRKTGSQY ; DIQDAIDKGL ; 2600: VDRKFFDQYR ; SGSLSLTQFA ; DMISLKNGVG ; NSSGLGGSVN ; DDVFSSSRHD ; 2650: SVSKISTISS ; VRNLTIRSSS ; LSDPLEESSP ; IAAIFDTENL ; EKISIAEGIE ; 2700: RGIVDSITGQ ; RLLEAQACTG ; GIIHPTTGQK ; LSLQDAVNQG ; LIDQDMATRL ; 2750: KPAQKAFIGF ; EGVKGKKKMS ; AAEAVKEKWL ; PYEAGQRFLE ; FQFLTGGLVD ; 2800: PEVHGRISTE ; EAIRKGFIDG ; RAAQRLQDIS ; SYAKILTCPK ; TKLKISYKDA ; 2850: MNRSMVEDIT ; GLRLLEAASV ; SSKGLPSPYN ; MSAPGSRSGS ; RSGSRSGSRS ; 2883: GSRSGSRRGS ; FDATGNSSYS ; YSYSFSSSSI ; GGY
Sequence Length	2883
Sub Unit	Homodimer. Interacts with COL17A1 (via cytoplasmic region). Associates (via C-terminal) with KRT5-KRT14 (via rod region), KRT8-KRT18 and VIM intermediate filaments.

Uniprot	E9Q557
Gene Name	Dsp
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:109620
Unigene	Mm.355327

Reference	1. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 2. "Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2836;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] tissue: Liver.

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