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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Coagulation factor XII

SKU : BHE13804389

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0694m
Alternative Names	Hageman factor ; HAF
Categories	Elisa
Function	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
Specificity	Natural and recombinant Mouse Coagulation factor XII
Subcellular Location	Secreted
Detection Range	0.312-20ng/mL
Entryname	FA12_MOUSE
Method Type	Sandwich
Platform	PF00008
Protein Name	Coagulation factor XII
Sensitivity	0.164ng/mL
Sequence	50: MTALLFLGSL ; LMSLDLTLSA ; PPWKDSKKFK ; DAPDGPTVVL ; TVDGRLCHFP ; 100: FQYHRQLHHK ; CIHKRRPGSR ; PWCATTPNFD ; EDQQWGYCLE ; PKKVKDHCSK ; 150: HNPCHKGGTC ; INTPNGPHCL ; CPEHLTGKHC ; QKEKCFEPQL ; LKFFHENELW ; 200: FRTGPGGVAR ; CECKGSEAHC ; KPVASQACSI ; NPCLNGGSCL ; LVEDHPLCRC ; 250: PTGYTGYFCD ; LDLWATCYEG ; RGLSYRGQAG ; TTQSGAPCQR ; WTVEATYRNM ; 300: TEKQALSWGL ; GHHAFCRNPD ; NDTRPWCFVW ; SGDRLSWDYC ; GLEQCQTPTF ; 350: APLVVPESQE ; ESPSQAPSLS ; HAPNDSTDHQ ; TSLSKTNTMG ; CGQRFRKGLS ; 400: SFMRVVGGLV ; ALPGSHPYIA ; ALYWGNNFCA ; GSLIAPCWVL ; TAAHCLQNRP ; 450: APEELTVVLG ; QDRHNQSCEW ; CQTLAVRSYR ; LHEGFSSITY ; QHDLALLRLQ ; 500: ESKTNSCAIL ; SPHVQPVCLP ; SGAAPPSETV ; LCEVAGWGHQ ; FEGAEEYSTF ; 550: LQEAQVPFIA ; LDRCSNSNVH ; GDAILPGMLC ; AGFLEGGTDA ; CQGDSGGPLV ; 597: CEEGTAEHQL ; TLRGVISWGS ; GCGDRNKPGV ; YTDVANYLAW ; IQKHIAS
Sequence Length	597
String	Q80YC5
Sub Unit	Interacts with HRG; the interaction, which is enhanced in the presence of zinc ions and inhibited by heparin-binding, inhibits factor XII autoactivation and contact-initiated coagulation.

Uniprot	Q80YC5
Gene Name	F12
Kegg	mmu:58992
Unigene	Mm.42224

Reference	1. Schloesser M., Schwager S., Engel W. Submitted (1996-07) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Liver. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: FVB/N. tissue: Liver.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804389	E0694m	96T	$776		Add to Cart

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