GRO/MGSA receptor ; High affinity interleukin-8 receptor B ; IL-8R B ; CD182 ; Cmkar2 ; Gpcr16 ; Il8rb
Categories
Elisa
Function
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Specificity
Natural and recombinant Mouse C-X-C chemokine receptor type 2