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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Bile acid receptor

SKU : BHE13808569

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2042m
Alternative Names	Farnesoid X-activated receptor ; Farnesol receptor HRR-1 ; Nuclear receptor subfamily 1 group H member 4 ; Retinoid X receptor-interacting protein 14 ; RXR-interacting protein 14 ; Bar ; Fxr ; Rip14
Categories	Elisa
Function	Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) and activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus.
Specificity	Natural and recombinant Mouse Bile acid receptor
Subcellular Location	Nucleus
Detection Range	78-5000pg/mL
Entryname	NR1H4_MOUSE
Method Type	Sandwich
Platform	PF00104
Protein Name	Bile acid receptor
Sensitivity	40pg/mL
Sequence	50: MVMQFQGLEN ; PIQISLHHSH ; RLSGFVPEGM ; SVKPAKGMLT ; EHAAGPLGQN ; 100: LDLESYSPYN ; NVPFPQVQPQ ; ISSSSYYSNL ; GFYPQQPEDW ; YSPGIYELRR ; 150: MPAETGYQGE ; TEVSEMPVTK ; KPRMAAASAG ; RIKGDELCVV ; CGDRASGYHY ; 200: NALTCEGCKG ; FFRRSITKNA ; VYKCKNGGNC ; VMDMYMRRKC ; QECRLRKCKE ; 250: MGMLAECMYT ; GLLTEIQCKS ; KRLRKNVKQH ; ADQTANEDDS ; EGRDLRQVTS ; 300: TTKFCREKTE ; LTADQQTLLD ; YIMDSYNKQR ; MPQEITNKIL ; KEEFSAEENF ; 350: LILTEMATSH ; VQILVEFTKK ; LPGFQTLDHE ; DQIALLKGSA ; VEAMFLRSAE ; 400: IFNKKLPAGH ; ADLLEERIRK ; SGISDEYITP ; MFSFYKSVGE ; LKMTQEEYAL ; 450: LTAIVILSPD ; RQYIKDREAV ; EKLQEPLLDV ; LQKLCKMYQP ; ENPQHFACLL ; 488: GRLTELRTFN ; HHHAEMLMSW ; RVNDHKFTPL ; LCEIWDVQ
Sequence Length	488
String	Q60641
Sub Unit	Interacts with CARM1 and SMARD1. After activation by agonist binding, interacts with a coactivator, NCOA1 or NCOA2 (By similarity) Heterodimer of NR1H4 and RXR.

Uniprot	Q60641
Gene Name	Nr1h4
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:20186
Unigene	Mm.3095

Reference	1. "Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors." Seol W., Choi H.S., Moore D.D. Mol. Endocrinol.9:72-85(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);INTERACTION WITH RXR tissue: Liver. 2. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2) tissue: Kidney.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808569	E2042m	96T	$776		Add to Cart

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